XOOMAR

Milestone Pharmaceuticals (MIST)

Milestone Pharmaceuticals on one page: short interest, daily short volume, fails to deliver, planned sales, large holders, 13F holders, earnings dates and insider trades. Listed on Nasdaq, classified by the SEC as pharmaceutical preparations.

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19.7M

Short interest

settlement 2026-10-15

18.7

Days to cover

+2.7 days vs prior

63.8%

Short share of volume

2026-11-02

6,070

Fails to deliver

settlement 2026-10-14

Wed 11 Nov

Next earnings

estimated date

$0

Insider flow, 90 days

0 buys, 0 sells

As of 2026-11-02.

Short interest

FINRA, twice a month. The newest 48 settlements in the table, 48 in the chart. JSON

As of 15 October 2026, short interest in MIST is 19,710,285 shares, up 1,348,602 shares over the last month. Over the last 48 readings it ranged from 398,732 shares (14 February 2025) to 19,710,285 shares (15 October 2026). The latest reading sits at the top of that range. At the reported average volume of 1.1M shares a day that is 18.7 days to cover.

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SettlementShares shortChangeAvg daily volumeDays to cover
2026-10-1519,710,285+3.7%1,052,76018.72
2026-09-3019,009,468+3.5%1,189,68415.98
2026-09-1518,361,683+5.8%1,733,08010.59
2026-08-3117,362,761+4.4%1,530,57911.34
2026-08-1416,636,852+6.1%1,769,7749.40
2026-07-3115,685,890+7.5%1,234,11212.71
2026-07-1514,584,446+15.8%1,073,49913.59
2026-06-3012,597,709+18.8%1,681,1527.49
2026-06-1510,604,847+15.4%1,220,7118.69
2026-05-299,186,849+22.8%1,169,6127.85
2026-05-157,484,287-4.2%1,754,0384.27
2026-04-307,809,686-24.4%1,309,0495.97
2026-04-1510,325,577+22.1%3,686,8392.80
2026-03-318,453,485-3.5%2,643,6703.20
2026-03-138,758,410+4.0%1,294,9106.76
2026-02-278,424,060+12.7%1,307,4426.44
2026-02-137,474,168-22.1%2,061,7073.63
2026-01-309,597,134+2.2%2,173,3724.42
2026-01-159,389,788+13.8%3,848,4342.44
2025-12-318,250,257+0.3%6,333,7771.30
2025-12-158,222,765+11.3%12,175,8671.00
2025-11-287,389,406+49.2%4,214,4771.75
2025-11-144,953,316+8.7%1,914,6372.59
2025-10-314,556,371-11.9%1,451,4993.14
2025-10-155,173,005+2.9%1,494,8203.46
2025-09-305,029,319-14.9%893,1015.63
2025-09-155,912,759+9.3%1,241,6924.76
2025-08-295,412,053-4.3%1,124,1334.81
2025-08-155,656,083+0.0%832,6946.79
2025-07-315,654,252+10.5%1,516,3283.73
2025-07-155,115,566+160.0%3,871,1411.32
2025-06-301,967,445-2.1%635,5623.10
2025-06-132,009,988-5.1%625,0933.22
2025-05-302,118,339+7.8%862,6622.46
2025-05-151,965,048-16.9%1,085,5731.81
2025-04-302,365,630-13.0%2,067,8791.14
2025-04-152,718,305+6.1%1,906,9961.43
2025-03-312,561,518+190.9%7,029,4171.00
2025-03-14880,568+18.6%1,676,9591.00
2025-02-28742,790+86.3%1,210,5111.00
2025-02-14398,732-17.2%864,6601.00
2025-01-31481,393-27.9%695,1901.00
2025-01-15667,868+31.0%690,4581.00
2024-12-31509,757-1.0%573,2381.00
2024-12-13514,782+11.9%436,4071.18
2024-11-29460,052+5.0%319,4931.44
2024-11-15438,272-3.6%687,9051.00
2024-10-31454,790+1.2%271,4881.68

Daily short volume

FINRA Reg SHO, the last 30 sessions. JSON

As of 2 November 2026, the short share of MIST volume is 63.8%, up 15.2 points over the last five sessions. Over the last 30 readings it ranged from 38.0% (13 October 2026) to 73.5% (14 October 2026). The latest reading is 9.3 points above the 30-session average of 54.4%, on 467K shares reported.

DateShort volumeTotal volumeShort shareExempt
2026-11-02298K467K63.8%0
2026-10-30179K387K46.4%0
2026-10-29243K503K48.3%0
2026-10-28292K532K54.8%0
2026-10-27238K516K46.1%0
2026-10-26239K493K48.5%225
2026-10-23427K887K48.1%2,500
2026-10-22125K291K43.1%0
2026-10-21199K387K51.4%2
2026-10-20154K336K45.7%800
2026-10-19250K376K66.4%1,385
2026-10-16263K634K41.4%12,143
2026-10-15342K585K58.5%25
2026-10-14342K466K73.5%0
2026-10-13304K800K38.0%10
2026-10-12430K763K56.4%0
2026-10-09589K868K67.8%0
2026-10-08621K931K66.7%500
2026-10-07364K559K65.2%5
2026-10-06536K856K62.6%0
2026-10-05385K649K59.3%0
2026-10-02260K547K47.6%50
2026-10-01250K440K56.8%0
2026-09-30452K853K53.0%0
2026-09-29399K633K63.0%8,168
2026-09-28123K247K50.0%0
2026-09-25428K797K53.7%2,700
2026-09-24779K1.4M54.2%6,065
2026-09-23477K964K49.5%21,000
2026-09-22706K1.3M53.4%11,048

Fails to deliver

SEC, the last 30 settlement dates with a fail. JSON

As of 14 October 2026, the fails-to-deliver balance in MIST is 6,070 shares, up 1,581 shares over the last settlement date. Over the last 30 readings it ranged from 3 shares (28 August 2026) to 145,582 shares (21 August 2026). The latest reading sits at the bottom of that range.

SettlementShares failedPriceValue
2026-10-146,070$0.77$5K
2026-10-084,489$0.76$3K
2026-10-071,395$0.76$1K
2026-10-057,845$0.81$6K
2026-10-0238,220$0.82$31K
2026-10-0110,268$0.87$9K
2026-09-302,976$0.82$2K
2026-09-2883,511$0.79$66K
2026-09-2597,011$0.79$77K
2026-09-2439,829$0.86$34K
2026-09-2398,537$0.92$91K
2026-09-17228$0.89$203
2026-09-16807$0.93$751
2026-09-1515,128$0.95$14K
2026-09-1457,424$0.98$56K
2026-09-111,778$1.05$2K
2026-09-1015,720$1.07$17K
2026-09-091,458$1.13$2K
2026-09-0819,643$1.20$24K
2026-09-0391,301$1.18$108K
2026-09-0279,995$1.14$91K
2026-09-0127,427$1.16$32K
2026-08-3120,410$1.16$24K
2026-08-283$1.19$4
2026-08-2560,485$1.04$63K
2026-08-21145,582$1.03$150K
2026-08-181,043$1.10$1K
2026-08-1486,918$1.07$93K
2026-08-1244,291$1.27$56K
2026-08-1117,379$1.26$22K

Insider trades

SEC Form 4, newest first. JSON

No open-market insider trades were reported for MIST in the last 90 days. The most recent filings are listed below. Latest filing: Oliveto Joseph (President and CEO) on 2026-04-16.

DateInsiderTitleTypeSharesPriceValueOwned after
2026-04-16Oliveto JosephPresident and CEOSell37K$2.26$82K446K
2026-01-26Oliveto JosephPresident and CEOExercise or conversion67Kprice not stated in the filingnot stated517K
2026-01-26Oliveto JosephPresident and CEOSell35K$1.93$67K483K
2026-01-26Hasija AmitCFO & EVP of Corp. DevelopmentExercise or conversion20Kprice not stated in the filingnot stated112K
2026-01-26Hasija AmitCFO & EVP of Corp. DevelopmentSell12K$1.93$24K100K
2026-01-26Muller LorenzChief Commercial OfficerSell11K$1.93$22K205K
2026-01-26Muller LorenzChief Commercial OfficerExercise or conversion20Kprice not stated in the filingnot stated217K
2026-01-26Nelson Jeffrey EdwardChief Operating OfficerSell12K$1.93$24K50K
2026-01-26Nelson Jeffrey EdwardChief Operating OfficerExercise or conversion20Kprice not stated in the filingnot stated62K
2026-01-26Bharucha DavidChief Medical OfficerExercise or conversion20Kprice not stated in the filingnot stated125K
2026-01-26Bharucha DavidChief Medical OfficerSell12K$1.93$24K113K
2026-01-08Oliveto JosephPresident and CEOSell43K$2.25$97K304K
2026-01-07Oliveto JosephPresident and CEOSell500$2.25$1K347K
2025-12-15Oliveto JosephPresident and CEOSell133K$2.32$309K451K
2025-12-15Hasija AmitCFO & EVP of Corp. DevelopmentSell58K$2.32$135K92K
2025-12-15Muller LorenzChief Commercial OfficerSell54K$2.32$124K196K
2025-12-15Nelson Jeffrey EdwardChief Operating OfficerSell58K$2.32$135K42K
2025-12-15Bharucha DavidChief Medical OfficerSell58K$2.32$135K105K
2025-12-12Oliveto JosephPresident and CEOGrant280Kprice not stated in the filingnot stated584K
2025-12-12Hasija AmitCFO & EVP of Corp. DevelopmentGrant100Kprice not stated in the filingnot stated150K
2025-12-12Muller LorenzChief Commercial OfficerGrant100Kprice not stated in the filingnot stated250K
2025-12-12Nelson Jeffrey EdwardChief Operating OfficerGrant100Kprice not stated in the filingnot stated100K
2025-12-12Bharucha DavidChief Medical OfficerGrant100Kprice not stated in the filingnot stated163K
2025-12-09Muller LorenzChief Commercial OfficerGift25K$0.00$0150K
2025-07-11PAPA JOSEPH CDirectorGrant100Kprice not stated in the filingnot stated100K
2025-07-11Muller LorenzChief Commercial OfficerGrant67Kprice not stated in the filingnot stated175K
2025-07-11Oliveto JosephPresident and CEOGrant67Kprice not stated in the filingnot stated347K
2025-07-11Bharucha DavidChief Medical OfficerGrant53Kprice not stated in the filingnot stated63K
2025-07-11Wills Robert JamesDirectorGrant50Kprice not stated in the filingnot stated65K
2025-07-11Hasija AmitCFO & EVP of Corp. DevelopmentGrant50Kprice not stated in the filingnot stated50K
2025-07-11Liebert Debra K.DirectorGrant17Kprice not stated in the filingnot stated17K
2023-03-22WONG RODERICKTenPercentOwnerOther transaction1.1Mprice not stated in the filingnot stated3.3M
2022-12-05Bharucha DavidChief Medical OfficerBuy7K$4.69$33K10K
2022-12-01Bharucha DavidChief Medical OfficerBuy3K$4.86$15K3K
2022-10-21Liebert Debra K.DirectorBuy4K$5.26$21K4K
2022-10-20Liebert Debra K.DirectorBuy10K$5.29$53K10K
2022-10-20Pasternak Richard CDirectorBuy10K$5.20$52K10K
2022-10-19TOMSICEK MICHAEL JOHNDirectorBuy15K$5.32$80K15K
2022-10-19Wills Robert JamesDirectorBuy15K$4.93$74K15K
2022-09-14Liebert Debra K.DirectorOther transaction127$0.00$0127
2022-09-07RTW INVESTMENTS, LPTenPercentOwnerSell1.6M$8.71$13.6M4.3M
2022-09-07RTW INVESTMENTS, LPTenPercentOwnerBuy1.6M$8.71$13.6M4.3M
2022-05-31TRUEX PAUL FDirectorExercise or conversion8K$1.12$9K8K
2022-05-31TRUEX PAUL FDirectorExercise or conversion45K$1.54$69K53K
2022-05-31TRUEX PAUL FDirectorExercise or conversion23K$1.54$35K76K
2022-05-31TRUEX PAUL FDirectorExercise or conversion822$2.66$2K77K
2022-05-31TRUEX PAUL FDirectorBuy5K$5.60$28K82K
2020-08-26Muller LorenzChief Commercial OfficerExercise or conversion6K$1.54$9K108K
2020-07-29FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBECTenPercentOwnerSell500K$8.32$4.2M2.3M
2020-07-28FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBECTenPercentOwnerSell20K$8.10$161K2.8M
2020-04-03Muller LorenzChief Commercial OfficerExercise or conversion33K$1.54$50K85K
2020-04-03Muller LorenzChief Commercial OfficerExercise or conversion18K$1.54$28K103K
2020-03-19RTW INVESTMENTS, LPTenPercentOwnerBuy6K$10.87$64K4.3M
2020-03-18RTW INVESTMENTS, LPTenPercentOwnerBuy3K$10.36$28K4.3M
2020-03-02RTW INVESTMENTS, LPTenPercentOwnerBuy78K$18.95$1.5M4.3M
2020-01-13WONG RODERICKTenPercentOwnerBuy270K$16.25$4.4M4.2M
2019-12-31RTW INVESTMENTS, LPTenPercentOwnerBuy21K$15.50$332K4.0M
2019-12-30RTW INVESTMENTS, LPTenPercentOwnerBuy1K$15.48$21K3.9M
2019-12-21Oliveto JosephPresident and CEOExercise or conversion7K$1.54$11K281K
2019-10-01Muller LorenzChief Commercial OfficerExercise or conversion3K$1.54$4K52K

Form 4 filings are due within two business days of the trade. Insiders sell for many reasons that say nothing about the company; open-market buys are rarer.

Planned sales (Form 144)

Newest first. JSON

3 Form 144 notices on file for MIST worth $252K at the prices reported; 0 in the last 90 days worth $0. Latest: JOSEPH OLIVETO filed on 2026-04-16 to sell 36,500 shares ($80K) from 2026-04-16.

FiledSellerSharesMarket valueOf outstandingSale fromBroker
2026-04-16JOSEPH OLIVETODirector, Officer37K$80K0.031%2026-04-16Morgan Stanley Smith Barney LLC Executive Financial Services
2026-01-08JOSEPH OLIVETODirector, Officer80K$171K0.093%2026-01-08Morgan Stanley Smith Barney LLC Executive Financial Services
2026-01-07JOSEPH OLIVETOOfficer500$1K0.001%2026-01-07Morgan Stanley Smith Barney LLC Executive Financial Services

Large holders (13D and 13G)

One row per reporting person with its latest filing, newest first. JSON

12 holders report 5% or more of MIST in their latest filing, all on Schedule 13G (passive). The largest reported stake is RTW Investments, LP at 9.9% of the class (12,356,953 shares), filed 2026-05-15 for an event on 2026-03-31.

FiledFormHolderSharesOf classEvent
2026-08-0713GPavaki Capital Management LLCinvestment adviser9.1M7.3%2025-12-31
2026-08-0713GPavaki Capital Partners, LPpartnership9.1M7.3%2025-12-31
2026-08-0713GAshok Rambhai Patelindividual, parent holding company9.1M7.3%2025-12-31
2026-05-1513G/Ano. 7RTW Investments, LPinvestment adviser, partnership12.4M9.9%2026-03-31
2026-05-1513G/Ano. 7Roderick Wongparent holding company, individual12.4M9.9%2026-03-31
2026-05-1313G/Ano. 1Adage Capital Management, L.P.investment adviser, partnership8.0M6.4%2026-03-31
2026-05-1313G/Ano. 1Robert Atchinsonparent holding company, individual8.0M6.4%2026-03-31
2026-05-1313G/Ano. 1Phillip Grossparent holding company, individual8.0M6.4%2026-03-31
2026-03-2613G/Ano. 2Trails Edge Capital Partners, LPinvestment adviser, partnership5.3M4.3%2026-03-20
2026-03-2613G/Ano. 2Trails Edge Biotechnology Master Fund, LPpartnership5.3M4.3%2026-03-20
2026-03-2613G/Ano. 2Ortav Yehudaiindividual5.3M4.3%2026-03-20
2025-12-2313GPropel Bio Management, LLCinvestment adviser8.9M9.9%2025-07-11
2025-12-2313GLeen Kawasindividual8.9M9.9%2025-07-11
2025-12-2313GRichard Kayneindividual8.9M9.9%2025-07-11
2025-12-2313GPropel Bio Partners LLCother entity8.9M9.9%2025-07-11

13F holders

Tracked managers holding MIST at their latest 13F. JSON

4 of the 30 tracked managers held MIST at their latest 13F, $14.2M in total at quarter-end prices. Point72 Asset Management is the largest at $7.3M (0.0% of its portfolio) as of 2026-06-30. Over the prior quarter 2 added shares and 2 cut.

FundQuarterSharesValueOf portfolioChange in shares
Point72 Asset Management2026-06-305.4M$7.3M0.01%+4.3M
Millennium Management2026-06-303.1M$4.2M0.00%+1.6M
Two Sigma Investments2026-06-302.0M$2.7M0.00%-277K
Citadel Advisors2026-06-3033K$44K0.00%-164K

Only the 30 tracked managers on the funds hub; a 13F reports long positions in US listed stock at quarter end, 45 days late, and says nothing about shorts or positions sold since.

What this page is

Milestone Pharmaceuticals in the regulatory record

Regulators publish company data in separate files that never sit next to each other: FINRA's twice-monthly short interest, its daily short sale volume, the SEC's fails-to-deliver counts, and each insider's Form 4. A company page puts those series for one ticker on one URL, with planned sales, large holders, 13F holders and financials beside them, so the short position, the daily flow, the settlement fails and what insiders are doing can be read together.

Each section has its own history table, a one-line summary of the latest figures and its own JSON and CSV links, and says when its source last updated.

This page follows Milestone Pharmaceuticals (MIST), SEC CIK 1408443, listed on Nasdaq, classified by the SEC as pharmaceutical preparations. The cross-market tables live on the short interest and insider transactions hubs.

Source and updates

Short interest
FINRA consolidated short interestSource: FINRA.Twice a month, about eight business days after settlement. Latest 2026-10-15.JSON and CSV
Daily short volume
FINRA Reg SHO daily filesSource: FINRA.Every trading day, the morning after FINRA posts it. Latest 2026-11-02.JSON and CSV
Fails to deliver
SEC fails-to-deliver dataSource: SEC.Twice a month, a few weeks after the half month ends. Latest 2026-10-14.JSON and CSV
Planned sales
SEC EDGAR Form 144Source: SEC.New notices appear shortly after the SEC posts them; a notice is filed on or before the sale. Latest 2026-04-16.JSON and CSV
Large holders
SEC EDGAR Schedule 13D and 13GSource: SEC.New filings appear shortly after the SEC posts them. A 13D is due within five business days of crossing 5%; a 13G follows the passive schedule. Latest 2026-08-07.JSON and CSV
13F holders
SEC EDGAR Form 13F-HRSource: SEC.Quarterly, filed within 45 days of quarter end; 30 tracked managers. Latest 2026-06-30.JSON and CSV
Earnings dates
SEC EDGAR 8-K filings (Item 2.02)Source: SEC.Twice a day. Reported dates come from the company's 8-K filings; the next date is marked as an estimate until the 8-K arrives. Latest 2026-08-12.JSON and CSV
Insider trades
SEC EDGAR Form 4Source: SEC.New filings appear shortly after the SEC posts them; they're due two business days after the trade. Latest 2026-04-16.JSON and CSV
Company record
EDGAR filing index for CIK 1408443Ticker, name and exchange from the SEC's company list, refreshed weekly.
Rate limits
10 requests a minute without a key, 30 with a free key from a free account.

How to read it

  • Read the position against the flow: rising short interest with a high daily short share is new shorting; rising short interest with a normal short share is old shorts holding on.
  • Insider buys next to a large short position are rare and stand out; insider sells next to one are common and mean little.
  • Fails to deliver matter relative to the float, not in absolute shares; a million failed shares in a mega cap is noise.

Analysis of what the data shows, not advice. XOOMAR does not recommend buying, selling or holding anything.

Datasets

Frequently Asked Questions

How much of MIST is sold short?
19,710,285 shares were held short at the 2026-10-15 settlement, 18.7 days of average volume. FINRA publishes the next count about eight business days after the 15th and the last business day of the month.
What is MIST's daily short volume?
On 2026-11-02, 297,547 of the 466,534 MIST shares reported to FINRA were sold short, 63.8% of the day's reported volume. Short volume is a flow for one day, not a position.
Does MIST have fails to deliver?
The SEC's latest file shows 6,070 MIST shares failed to deliver at settlement 2026-10-14. Fails are reported per settlement date and published twice a month with a lag.
Are MIST insiders buying or selling?
No open-market insider trades were reported for MIST in the last 90 days. The most recent filings are listed below. Latest filing: Oliveto Joseph (President and CEO) on 2026-04-16.
Have MIST insiders filed to sell?
3 Form 144 notices on file for MIST worth $252K at the prices reported; 0 in the last 90 days worth $0. Latest: JOSEPH OLIVETO filed on 2026-04-16 to sell 36,500 shares ($80K) from 2026-04-16.
Who owns 5% or more of MIST?
12 holders report 5% or more of MIST in their latest filing, all on Schedule 13G (passive). The largest reported stake is RTW Investments, LP at 9.9% of the class (12,356,953 shares), filed 2026-05-15 for an event on 2026-03-31.
Which tracked 13F managers own MIST?
4 of the 30 tracked 13F managers held MIST shares at their latest filing, $14.2M in all. The largest: Steve Cohen's Point72 Asset Management (5.4M shares, $7.3M), Izzy Englander's Millennium Management (3.1M shares, $4.2M), Two Sigma Investments (2.0M shares, $2.7M), Ken Griffin's Citadel Advisors (33K shares, $44K).

Data on this page is provided for informational purposes only and is not financial advice. See our editorial policy.