Spruce Biosciences (SPRB)
Spruce Biosciences on one page: short interest, daily short volume, fails to deliver, large holders, 13F holders, earnings dates and insider trades. Listed on Nasdaq, classified by the SEC as pharmaceutical preparations.
522K
Short interest
settlement 2026-10-15
6.6
Days to cover
+2.1 days vs prior
50.4%
Short share of volume
2026-11-02
713
Fails to deliver
settlement 2026-10-06
Mon 9 Nov
Next earnings
estimated date
$0
Insider flow, 90 days
0 buys, 0 sells
As of 2026-11-02.
Short interest
FINRA, twice a month. The newest 48 settlements in the table, 48 in the chart. JSONAs of 15 October 2026, short interest in SPRB is 522,120 shares, up 105,980 shares over the last month. Over the last 48 readings it ranged from 618 shares (15 September 2025) to 522,120 shares (15 October 2026). The latest reading sits at the top of that range. At the reported average volume of 79K shares a day that is 6.6 days to cover.
Embed this chart.The embed keeps its attribution line.
<iframe src="https://xoomar.com/embed/stocks/sprb" width="100%" height="440" style="border:0;max-width:100%" loading="lazy" title="XOOMAR chart"></iframe>
| Settlement | Shares short | Change | Avg daily volume | Days to cover |
|---|---|---|---|---|
| 2026-10-15 | 522,120 | +21.0% | 78,847 | 6.62 |
| 2026-09-30 | 431,541 | +3.7% | 95,333 | 4.53 |
| 2026-09-15 | 416,140 | -5.5% | 125,092 | 3.33 |
| 2026-08-31 | 440,243 | +9.2% | 73,685 | 5.97 |
| 2026-08-14 | 403,031 | -6.1% | 38,681 | 10.42 |
| 2026-07-31 | 429,122 | +3.2% | 56,447 | 7.60 |
| 2026-07-15 | 415,860 | +15.7% | 68,263 | 6.09 |
| 2026-06-30 | 359,389 | +36.9% | 114,015 | 3.15 |
| 2026-06-15 | 262,616 | +8.6% | 50,060 | 5.25 |
| 2026-05-29 | 241,927 | +12.5% | 57,262 | 4.22 |
| 2026-05-15 | 215,061 | +4.3% | 36,766 | 5.85 |
| 2026-04-30 | 206,110 | +14.2% | 118,464 | 1.74 |
| 2026-04-15 | 180,537 | +5.7% | 71,585 | 2.52 |
| 2026-03-31 | 170,814 | +25.1% | 36,272 | 4.71 |
| 2026-03-13 | 136,507 | +9.9% | 35,885 | 3.80 |
| 2026-02-27 | 124,200 | +59.3% | 62,244 | 2.00 |
| 2026-02-13 | 77,946 | +8.6% | 36,509 | 2.13 |
| 2026-01-30 | 71,745 | +17.3% | 24,008 | 2.99 |
| 2026-01-15 | 61,191 | -17.6% | 34,456 | 1.78 |
| 2025-12-31 | 74,248 | -15.7% | 33,974 | 2.19 |
| 2025-12-15 | 88,112 | -13.6% | 129,062 | 1.00 |
| 2025-11-28 | 102,021 | +17.4% | 179,085 | 1.00 |
| 2025-11-14 | 86,921 | -28.5% | 181,805 | 1.00 |
| 2025-10-31 | 121,620 | +493.3% | 159,159 | 1.00 |
| 2025-10-15 | 20,500 | +262.3% | 2,626,105 | 1.00 |
| 2025-09-30 | 5,658 | +815.5% | 16,945 | 1.00 |
| 2025-09-15 | 618 | +43.4% | 34,440 | 1.00 |
| 2025-07-31 | 83,130 | +96.7% | 442,683 | 1.00 |
| 2025-07-15 | 42,274 | -8.1% | 785,266 | 1.00 |
| 2025-06-30 | 45,987 | +43.4% | 353,521 | 1.00 |
| 2025-06-13 | 32,080 | +2.8% | 868,553 | 1.00 |
| 2025-05-30 | 31,198 | +72.7% | 231,769 | 1.00 |
| 2025-05-15 | 18,061 | -95.9% | 1,042,599 | 1.00 |
| 2025-04-30 | 437,154 | -14.6% | 4,680,815 | 1.00 |
| 2025-04-15 | 511,923 | +275.3% | 3,119,167 | 1.00 |
| 2025-03-31 | 136,392 | -48.7% | 162,713 | 1.00 |
| 2025-03-14 | 265,819 | -37.5% | 217,406 | 1.22 |
| 2025-02-28 | 425,082 | -5.0% | 404,074 | 1.05 |
| 2025-02-14 | 447,287 | +81.4% | 441,506 | 1.01 |
| 2025-01-31 | 246,580 | -44.6% | 241,310 | 1.02 |
| 2025-01-15 | 444,882 | +315.5% | 742,547 | 1.00 |
| 2024-12-31 | 107,071 | -51.1% | 458,121 | 1.00 |
| 2024-12-13 | 218,979 | +613.8% | 1,276,620 | 1.00 |
| 2024-11-29 | 30,676 | -56.8% | 291,231 | 1.00 |
| 2024-11-15 | 71,034 | -69.5% | 262,812 | 1.00 |
| 2024-10-31 | 232,773 | -18.4% | 564,743 | 1.00 |
| 2024-10-15 | 285,206 | -20.8% | 381,434 | 1.00 |
| 2024-09-30 | 359,889 | +44.5% | 573,272 | 1.00 |
Daily short volume
FINRA Reg SHO, the last 30 sessions. JSONAs of 2 November 2026, the short share of SPRB volume is 50.4%, down 4.5 points over the last five sessions. Over the last 30 readings it ranged from 42.2% (2 October 2026) to 88.8% (29 September 2026). The latest reading is 17.5 points below the 30-session average of 68.0%, on 42K shares reported.
| Date | Short volume | Total volume | Short share | Exempt |
|---|---|---|---|---|
| 2026-11-02 | 21K | 42K | 50.4% | 0 |
| 2026-10-30 | 23K | 35K | 64.6% | 0 |
| 2026-10-29 | 33K | 53K | 61.8% | 0 |
| 2026-10-28 | 10K | 15K | 69.2% | 0 |
| 2026-10-27 | 30K | 40K | 75.2% | 0 |
| 2026-10-26 | 22K | 40K | 54.9% | 0 |
| 2026-10-23 | 17K | 31K | 55.6% | 0 |
| 2026-10-22 | 39K | 54K | 71.3% | 0 |
| 2026-10-21 | 23K | 29K | 77.1% | 0 |
| 2026-10-20 | 14K | 21K | 63.7% | 0 |
| 2026-10-19 | 18K | 28K | 62.7% | 0 |
| 2026-10-16 | 24K | 42K | 57.6% | 0 |
| 2026-10-15 | 18K | 25K | 71.2% | 0 |
| 2026-10-14 | 40K | 54K | 73.0% | 0 |
| 2026-10-13 | 30K | 37K | 80.6% | 0 |
| 2026-10-12 | 33K | 39K | 86.0% | 0 |
| 2026-10-09 | 24K | 37K | 65.9% | 0 |
| 2026-10-08 | 19K | 22K | 84.9% | 0 |
| 2026-10-07 | 11K | 17K | 67.1% | 0 |
| 2026-10-06 | 19K | 36K | 53.2% | 0 |
| 2026-10-05 | 16K | 22K | 71.3% | 0 |
| 2026-10-02 | 12K | 30K | 42.2% | 0 |
| 2026-10-01 | 16K | 28K | 56.5% | 0 |
| 2026-09-30 | 10K | 16K | 60.0% | 0 |
| 2026-09-29 | 28K | 32K | 88.8% | 0 |
| 2026-09-28 | 10K | 13K | 73.8% | 0 |
| 2026-09-25 | 11K | 12K | 88.6% | 0 |
| 2026-09-24 | 13K | 15K | 88.5% | 0 |
| 2026-09-23 | 35K | 62K | 55.7% | 0 |
| 2026-09-22 | 23K | 34K | 67.7% | 0 |
Fails to deliver
SEC, the last 30 settlement dates with a fail. JSONAs of 6 October 2026, the fails-to-deliver balance in SPRB is 713 shares, up 618 shares over the last settlement date. Over the last 30 readings it ranged from 85 shares (18 August 2026) to 16,913 shares (7 July 2026). The latest reading sits at the bottom of that range.
| Settlement | Shares failed | Price | Value |
|---|---|---|---|
| 2026-10-06 | 713 | $45.42 | $32K |
| 2026-09-30 | 95 | $47.27 | $4K |
| 2026-09-28 | 699 | $48.72 | $34K |
| 2026-09-25 | 1,301 | $49.02 | $64K |
| 2026-09-24 | 256 | $49.42 | $13K |
| 2026-09-21 | 804 | $53.05 | $43K |
| 2026-09-11 | 1,467 | $54.35 | $80K |
| 2026-08-28 | 509 | $63.30 | $32K |
| 2026-08-26 | 3,227 | $63.40 | $205K |
| 2026-08-19 | 295 | $52.85 | $16K |
| 2026-08-18 | 85 | $52.92 | $4K |
| 2026-08-14 | 177 | $49.77 | $9K |
| 2026-08-11 | 546 | $46.20 | $25K |
| 2026-08-07 | 984 | $46.42 | $46K |
| 2026-08-06 | 100 | $46.61 | $5K |
| 2026-08-03 | 399 | $42.83 | $17K |
| 2026-07-30 | 110 | $41.45 | $5K |
| 2026-07-24 | 131 | $44.99 | $6K |
| 2026-07-21 | 187 | $44.50 | $8K |
| 2026-07-20 | 13,025 | $43.54 | $567K |
| 2026-07-17 | 3,846 | $44.28 | $170K |
| 2026-07-16 | 4,397 | $45.44 | $200K |
| 2026-07-15 | 7,172 | $46.36 | $332K |
| 2026-07-14 | 3,944 | $48.38 | $191K |
| 2026-07-13 | 1,621 | $50.07 | $81K |
| 2026-07-10 | 397 | $51.74 | $21K |
| 2026-07-09 | 911 | $49.80 | $45K |
| 2026-07-08 | 16,427 | $50.77 | $834K |
| 2026-07-07 | 16,913 | $51.85 | $877K |
| 2026-07-06 | 180 | $52.51 | $9K |
Insider trades
SEC Form 4, newest first. JSONNo open-market insider trades were reported for SPRB in the last 90 days. The most recent filings are listed below. Latest filing: Szwarcberg Javier B. (CHIEF EXECUTIVE OFFICER) on 2026-06-30.
| Date | Insider | Title | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|---|
| 2026-06-30 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Grant | 266 | $4.53 | $1K | 19K |
| 2025-12-31 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Grant | 5K | $4.53 | $21K | 19K |
| 2025-12-15 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 608 | $80.67 | $49K | 14K |
| 2025-12-15 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 1K | $0.00 | $0 | 15K |
| 2025-12-15 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 752 | $80.67 | $61K | 14K |
| 2025-12-15 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 1K | $0.00 | $0 | 14K |
| 2025-12-15 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 184 | $80.67 | $15K | 8K |
| 2025-12-15 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 513 | $0.00 | $0 | 8K |
| 2025-12-15 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 178 | $80.67 | $14K | 8K |
| 2025-12-15 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 496 | $0.00 | $0 | 8K |
| 2025-12-11 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 2K | $88.41 | $194K | 13K |
| 2025-12-11 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 5K | $0.00 | $0 | 15K |
| 2025-12-11 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 680 | $88.41 | $60K | 8K |
| 2025-12-11 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 2K | $0.00 | $0 | 8K |
| 2025-12-11 | Ways Douglas Kirk | Interim Chief Medical Officer | Exercise or conversion | 1K | $0.00 | $0 | 1K |
| 2025-12-10 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 428 | $85.67 | $37K | 10K |
| 2025-12-10 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 1K | $0.00 | $0 | 11K |
| 2025-12-10 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 184 | $85.67 | $16K | 6K |
| 2025-12-10 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 514 | $0.00 | $0 | 7K |
| 2025-10-20 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 2K | $148.16 | $228K | 9K |
| 2025-10-20 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 5K | $0.00 | $0 | 11K |
| 2025-10-20 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 661 | $148.16 | $98K | 6K |
| 2025-10-20 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 2K | $0.00 | $0 | 7K |
| 2025-10-06 | Parkman Healthcare Partners LLC | 10% owner | Sell | 25 | $17.46 | $436 | 1K |
| 2025-10-06 | Parkman Healthcare Partners LLC | 10% owner | Sell | 232 | $19.33 | $4K | 1K |
| 2025-10-06 | Parkman Healthcare Partners LLC | 10% owner | Buy | 256 | $17.91 | $5K | 1K |
| 2024-12-16 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 90K | $0.00 | $0 | 428K |
| 2024-12-16 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 32K | $0.39 | $12K | 396K |
| 2024-12-16 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 111K | $0.00 | $0 | 507K |
| 2024-12-16 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 40K | $0.39 | $15K | 467K |
| 2024-12-16 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 13K | $0.39 | $5K | 351K |
| 2024-12-16 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 39K | $0.00 | $0 | 340K |
| 2024-12-16 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 37K | $0.00 | $0 | 364K |
| 2024-12-16 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 14K | $0.39 | $5K | 327K |
| 2024-12-16 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Exercise or conversion | 27K | $0.00 | $0 | 150K |
| 2024-12-16 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Exercise or conversion | 32K | $0.00 | $0 | 173K |
| 2024-12-16 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Tax withholding | 9K | $0.39 | $4K | 141K |
| 2024-12-16 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Tax withholding | 11K | $0.39 | $4K | 161K |
| 2024-12-10 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Tax withholding | 128K | $0.54 | $69K | 338K |
| 2024-12-10 | Szwarcberg Javier B. | CHIEF EXECUTIVE OFFICER | Exercise or conversion | 359K | $0.00 | $0 | 466K |
| 2024-12-10 | Gharib Samir M. | PRESIDENT AND CFO | Exercise or conversion | 154K | $0.00 | $0 | 357K |
| 2024-12-10 | Gharib Samir M. | PRESIDENT AND CFO | Tax withholding | 55K | $0.54 | $30K | 302K |
| 2024-12-10 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Exercise or conversion | 106K | $0.00 | $0 | 162K |
| 2024-12-10 | Charlton Ralph William III | CHIEF MEDICAL OFFICER | Tax withholding | 38K | $0.54 | $21K | 124K |
| 2024-03-21 | Novo Holdings A/S | TenPercentOwner | Sell | 465K | $0.75 | $349K | 2.5M |
| 2024-03-20 | Novo Holdings A/S | TenPercentOwner | Sell | 360K | $0.73 | $263K | 3.0M |
| 2024-03-19 | Novo Holdings A/S | TenPercentOwner | Sell | 593K | $0.76 | $451K | 3.4M |
| 2024-03-18 | Novo Holdings A/S | TenPercentOwner | Sell | 842K | $0.77 | $648K | 4.0M |
| 2024-03-14 | Novo Holdings A/S | TenPercentOwner | Sell | 1.9M | $0.89 | $1.7M | 4.8M |
| 2023-12-29 | Gharib Samir M. | President & CFO | Grant | 11K | $0.98 | $11K | 203K |
| 2023-12-29 | Charlton Ralph William III | Chief Medical Officer | Grant | 9K | $0.98 | $9K | 55K |
| 2023-12-15 | Szwarcberg Javier B. | Chief Executive Officer | Exercise or conversion | 111K | $0.00 | $0 | 146K |
| 2023-12-15 | Szwarcberg Javier B. | Chief Executive Officer | Tax withholding | 38K | $1.66 | $64K | 107K |
| 2023-12-15 | Gharib Samir M. | President & CFO | Tax withholding | 23K | $1.66 | $39K | 167K |
| 2023-12-15 | Gharib Samir M. | President & CFO | Exercise or conversion | 75K | $0.00 | $0 | 190K |
| 2023-12-15 | Gharib Samir M. | President & CFO | Exercise or conversion | 37K | $0.00 | $0 | 204K |
| 2023-12-15 | Gharib Samir M. | President & CFO | Tax withholding | 13K | $1.66 | $21K | 192K |
| 2023-12-15 | Charlton Ralph William III | Chief Medical Officer | Exercise or conversion | 32K | $0.00 | $0 | 57K |
| 2023-12-15 | Charlton Ralph William III | Chief Medical Officer | Tax withholding | 11K | $1.66 | $18K | 46K |
| 2023-06-30 | Gharib Samir M. | President & CFO | Grant | 10K | $0.98 | $10K | 66K |
| 2023-06-30 | Gharib Samir M. | President & CFO | Exercise or conversion | 75K | price not stated in the filing | not stated | 141K |
| 2023-06-30 | Gharib Samir M. | President & CFO | Tax withholding | 26K | $2.15 | $56K | 115K |
| 2023-06-30 | Szwarcberg Javier B. | Chief Executive Officer | Grant | 20K | $0.98 | $20K | 35K |
| 2023-06-30 | Charlton Ralph William III | Chief Medical Officer | Grant | 12K | $0.98 | $12K | 25K |
| 2023-02-16 | O'Donnell Niall | Director | Buy | 630K | $3.17 | $2.0M | 1.3M |
| 2023-02-16 | Novo Holdings A/S | TenPercentOwner | Buy | 2.2M | $3.17 | $7.0M | 6.7M |
| 2023-01-03 | Gharib Samir M. | President & CFO | Tax withholding | 15K | $1.15 | $18K | 56K |
| 2023-01-03 | Gharib Samir M. | President & CFO | Exercise or conversion | 38K | price not stated in the filing | not stated | 71K |
| 2022-12-30 | Gharib Samir M. | President & CFO | Grant | 1 | $0.93 | $1 | 34K |
| 2022-12-30 | Szwarcberg Javier B. | Chief Executive Officer | Grant | 15K | $0.93 | $14K | 15K |
| 2022-12-30 | Charlton Ralph William III | Chief Medical Officer | Grant | 13K | $0.93 | $12K | 13K |
| 2022-06-30 | Gharib Samir M. | President & CFO | Exercise or conversion | 38K | price not stated in the filing | not stated | 41K |
| 2022-06-30 | Gharib Samir M. | President & CFO | Grant | 5K | $1.48 | $8K | 47K |
| 2022-06-30 | Gharib Samir M. | President & CFO | Tax withholding | 13K | $1.74 | $23K | 34K |
| 2021-12-31 | Gharib Samir M. | President & CFO | Other transaction | 2K | $3.79 | $8K | 5K |
| 2021-06-30 | Gharib Samir M. | Chief Financial Officer | Other transaction | 1K | $9.53 | $13K | 1K |
| 2021-06-30 | KING RICHARD | Chief Executive Officer | Other transaction | 2K | $9.53 | $21K | 2K |
| 2021-05-20 | SIMPSON CAMILLA V | Director | Exercise or conversion | 334 | $0.85 | $284 | 334 |
| 2021-05-20 | SIMPSON CAMILLA V | Director | Sell | 334 | $15.29 | $5K | 0 |
| 2021-05-19 | Novo Holdings A/S | TenPercentOwner | Sell | 475K | $13.90 | $6.6M | 4.5M |
| 2021-04-30 | SIMPSON CAMILLA V | Director | Sell | 14K | $16.14 | $227K | 0 |
| 2021-04-30 | SIMPSON CAMILLA V | Director | Exercise or conversion | 14K | $0.85 | $12K | 14K |
| 2020-10-14 | HANSSON JONAS | Director | Buy | 250K | $15.00 | $3.8M | 2.0M |
| 2020-10-14 | HANSSON JONAS | Director | Conversion | 1.8M | price not stated in the filing | not stated | 1.8M |
| 2020-10-14 | HealthCap VIII, L.P. | Other | Conversion | 1.8M | price not stated in the filing | not stated | 1.8M |
| 2020-10-14 | HealthCap VIII, L.P. | Other | Buy | 250K | $15.00 | $3.8M | 2.0M |
| 2020-10-14 | Chaya Moghrabi Dina | Director | Buy | 250K | $15.00 | $3.8M | 2.2M |
| 2020-10-14 | Chaya Moghrabi Dina | Director | Conversion | 1.9M | price not stated in the filing | not stated | 1.9M |
| 2020-10-14 | Omega Fund VI GP Manager, Ltd. | TenPercentOwner | Buy | 250K | $15.00 | $3.8M | 2.2M |
| 2020-10-14 | Omega Fund VI GP Manager, Ltd. | TenPercentOwner | Conversion | 1.9M | price not stated in the filing | not stated | 1.9M |
| 2020-10-14 | O'Donnell Niall | Director | Conversion | 446K | price not stated in the filing | not stated | 446K |
| 2020-10-14 | O'Donnell Niall | Director | Buy | 250K | $15.00 | $3.8M | 696K |
| 2020-10-14 | Muralidhar Bali | Director | Buy | 200K | $15.00 | $3.0M | 1.8M |
| 2020-10-14 | Muralidhar Bali | Director | Conversion | 1.6M | price not stated in the filing | not stated | 1.6M |
| 2020-10-14 | RiverVest Venture Fund III, L.P. | TenPercentOwner | Conversion | 828K | price not stated in the filing | not stated | 1.9M |
| 2020-10-14 | RiverVest Venture Fund III, L.P. | TenPercentOwner | Buy | 250K | $15.00 | $3.8M | 2.1M |
| 2020-10-14 | RiverVest Venture Fund III, L.P. | TenPercentOwner | Conversion | 1.1M | price not stated in the filing | not stated | 1.1M |
| 2020-10-14 | Novo Holdings A/S | TenPercentOwner | Conversion | 4.7M | price not stated in the filing | not stated | 4.7M |
| 2020-10-14 | Novo Holdings A/S | TenPercentOwner | Buy | 250K | $15.00 | $3.8M | 5.0M |
Form 4 filings are due within two business days of the trade. Insiders sell for many reasons that say nothing about the company; open-market buys are rarer.
Large holders (13D and 13G)
One row per reporting person with its latest filing, newest first. JSON9 holders report 5% or more of SPRB in their latest filing, all on Schedule 13G (passive). The largest reported stake is AIGH Capital Management LLC at 9.1% of the class (250,000 shares), filed 2026-07-27 for an event on 2026-06-30.
| Filed | Form | Holder | Shares | Of class | Event |
|---|---|---|---|---|---|
| 2026-08-14 | 13G | AWM Investment Company, Inc.investment adviser | 147K | 5.1% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 1 | ADAR1 Capital Management, LLCinvestment adviser, other entity | 68K | 2.5% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 1 | Daniel Schneebergerparent holding company, individual | 68K | 2.5% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Kenneth Griffinparent holding company, individual | 52K | 1.9% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel Advisors LLCinvestment adviser, parent holding company, other entity | 47K | 1.7% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel Advisors Holdings LPparent holding company, partnership | 47K | 1.7% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel GP LLCparent holding company, other entity | 47K | 1.7% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel Securities Group LPparent holding company, partnership | 5K | 0.2% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel Securities GP LLCparent holding company, other entity | 5K | 0.2% | 2026-06-30 |
| 2026-08-14 | 13G/Ano. 3 | Citadel Securities LLCbroker-dealer, other entity | 2K | 0.1% | 2026-06-30 |
| 2026-08-14 | 13G | OrbiMed Advisors LLCinvestment adviser | 132K | 4.8% | 2026-06-30 |
| 2026-08-14 | 13G | OrbiMed Capital LLCinvestment adviser | 68K | 2.5% | 2026-06-30 |
| 2026-08-04 | 13G/Ano. 1 | Integrated Core Strategies (US) LLCother entity | 161K | 5.8% | 2026-06-30 |
| 2026-08-04 | 13G/Ano. 1 | Millennium Management LLCother entity | 161K | 5.8% | 2026-06-30 |
| 2026-08-04 | 13G/Ano. 1 | Millennium Group Management LLCother entity | 161K | 5.8% | 2026-06-30 |
| 2026-08-04 | 13G/Ano. 1 | Israel A. Englanderindividual | 161K | 5.8% | 2026-06-30 |
| 2026-07-30 | 13G | BlackRock, Inc.parent holding company | 188K | 6.8% | 2026-06-30 |
| 2026-07-27 | 13G | AIGH Capital Management LLCinvestment adviser, other entity | 250K | 9.1% | 2026-06-30 |
| 2026-07-27 | 13G | Orin Hirschmanparent holding company, individual | 250K | 9.1% | 2026-06-30 |
| 2026-05-15 | 13G/Ano. 2 | William Blankparent holding company, individual | 12K | 0.9% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 2 | Squadron Master Fund LPpartnership | 12K | 0.9% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 2 | Squadron Capital Management LLCinvestment adviser, parent holding company | 12K | 0.9% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 2 | Matthew Sesterhennparent holding company, individual | 12K | 0.9% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Alyeska Investment Group, L.P.investment adviser | 62K | 4.5% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Alyeska Fund GP, LLCother entity | 62K | 4.5% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Anand Parekhindividual | 62K | 4.5% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Wellington Group Holdings LLPparent holding company | 49K | 3.6% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Wellington Management Group LLPparent holding company | 49K | 3.6% | 2026-03-31 |
| 2026-05-15 | 13G/Ano. 1 | Wellington Investment Advisors Holdings LLPparent holding company | 49K | 3.6% | 2026-03-31 |
| 2026-05-07 | 13G/Ano. 2 | Neil Shahrestaniindividual, parent holding company | 121K | 4.8% | 2026-04-30 |
| 2026-05-07 | 13G/Ano. 2 | Ikarian Capital, LLCinvestment adviser | 121K | 4.8% | 2026-04-30 |
| 2026-04-28 | 13G | Michael Gelbandindividual, parent holding company | 22K | 0.8% | 2026-04-22 |
| 2026-04-28 | 13G | ExodusPoint Capital Management, LPinvestment adviser, partnership | 22K | 0.8% | 2026-04-22 |
| 2026-04-28 | 13G | ExodusPoint Capital Partners GP, LLCcorporation, parent holding company | 22K | 0.8% | 2026-04-22 |
| 2026-02-18 | 13D/Ano. 3 | Abingworth Bioventures VII LPpartnership | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Abingworth LLPpartnership | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | The Carlyle Group Inc.corporation | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Carlyle Holdings I GP Inc.corporation | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Carlyle Holdings I GP Sub L.L.C.other entity | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Carlyle Holdings I L.P.partnership | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | CG Subsidiary Holdings L.L.C.other entity | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | TC Group, L.L.C.other entity | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Carlyle Investment Management L.L.C.other entity | 51K | 4.7% | 2026-02-18 |
| 2026-02-18 | 13D/Ano. 3 | Carlyle Genesis UK LLCother entity | 51K | 4.7% | 2026-02-18 |
| 2025-11-24 | 13G | Boone Peter David Mrindividual | 68K | 6.4% | 2025-11-21 |
| 2025-10-09 | 13D/Ano. 3 | HealthCap VIII, L.P.partnership | 37K | 3.4% | 2025-10-07 |
| 2025-10-09 | 13D/Ano. 3 | HealthCap VIII GP LLCpartnership | 37K | 3.4% | 2025-10-07 |
13F holders
Tracked managers holding SPRB at their latest 13F. JSON4 of the 30 tracked managers held SPRB at their latest 13F, $13.3M in total at quarter-end prices. Millennium Management is the largest at $8.7M (0.0% of its portfolio) as of 2026-06-30. Over the prior quarter 3 added shares and 1 cut.
| Fund | Quarter | Shares | Value | Of portfolio | Change in shares |
|---|---|---|---|---|---|
| Millennium Management | 2026-06-30 | 161K | $8.7M | 0.00% | +49K |
| Citadel Advisors | 2026-06-30 | 52K | $2.8M | 0.00% | -18K |
| Point72 Asset Management | 2026-06-30 | 28K | $1.5M | 0.00% | new |
| Renaissance Technologies | 2026-06-30 | 5K | $254K | 0.00% | new |
Only the 30 tracked managers on the funds hub; a 13F reports long positions in US listed stock at quarter end, 45 days late, and says nothing about shorts or positions sold since.
What this page is
Spruce Biosciences in the regulatory record
Regulators publish company data in separate files that never sit next to each other: FINRA's twice-monthly short interest, its daily short sale volume, the SEC's fails-to-deliver counts, and each insider's Form 4. A company page puts those series for one ticker on one URL, with planned sales, large holders, 13F holders and financials beside them, so the short position, the daily flow, the settlement fails and what insiders are doing can be read together.
Each section has its own history table, a one-line summary of the latest figures and its own JSON and CSV links, and says when its source last updated.
This page follows Spruce Biosciences (SPRB), SEC CIK 1683553, listed on Nasdaq, classified by the SEC as pharmaceutical preparations. The cross-market tables live on the short interest and insider transactions hubs.
Source and updates
- Short interest
- FINRA consolidated short interestSource: FINRA.Twice a month, about eight business days after settlement. Latest 2026-10-15.JSON and CSV
- Daily short volume
- FINRA Reg SHO daily filesSource: FINRA.Every trading day, the morning after FINRA posts it. Latest 2026-11-02.JSON and CSV
- Fails to deliver
- SEC fails-to-deliver dataSource: SEC.Twice a month, a few weeks after the half month ends. Latest 2026-10-06.JSON and CSV
- Large holders
- SEC EDGAR Schedule 13D and 13GSource: SEC.New filings appear shortly after the SEC posts them. A 13D is due within five business days of crossing 5%; a 13G follows the passive schedule. Latest 2026-08-14.JSON and CSV
- 13F holders
- SEC EDGAR Form 13F-HRSource: SEC.Quarterly, filed within 45 days of quarter end; 30 tracked managers. Latest 2026-06-30.JSON and CSV
- Earnings dates
- SEC EDGAR 8-K filings (Item 2.02)Source: SEC.Twice a day. Reported dates come from the company's 8-K filings; the next date is marked as an estimate until the 8-K arrives. Latest 2026-08-12.JSON and CSV
- Insider trades
- SEC EDGAR Form 4Source: SEC.New filings appear shortly after the SEC posts them; they're due two business days after the trade. Latest 2026-06-30.JSON and CSV
- Company record
- EDGAR filing index for CIK 1683553Ticker, name and exchange from the SEC's company list, refreshed weekly.
- Rate limits
- 10 requests a minute without a key, 30 with a free key from a free account.
How to read it
- Read the position against the flow: rising short interest with a high daily short share is new shorting; rising short interest with a normal short share is old shorts holding on.
- Insider buys next to a large short position are rare and stand out; insider sells next to one are common and mean little.
- Fails to deliver matter relative to the float, not in absolute shares; a million failed shares in a mega cap is noise.
Analysis of what the data shows, not advice. XOOMAR does not recommend buying, selling or holding anything.
Other companies the SEC classifies as pharmaceutical preparations
Other company pages
- STESTERIS
- STLDSteel Dynamics
- STRCStrategy
- STRLSterling Infrastructure
- STTState Street
- STXSeagate Technology Holdings
- STZConstellation Brands
- SUISun Communities
- SUNBSunbelt Rentals Holdings
- SWSmurfit Westrock
- SWKStanley Black & Decker
- SWKSSkyworks Solutions
- SXTCChina SXT Pharmaceuticals
- SYFSynchrony Financial
- SYKStryker
- SYNASynaptics
Datasets
Frequently Asked Questions
How much of SPRB is sold short?
What is SPRB's daily short volume?
Does SPRB have fails to deliver?
Are SPRB insiders buying or selling?
Who owns 5% or more of SPRB?
Which tracked 13F managers own SPRB?
Data on this page is provided for informational purposes only and is not financial advice. See our editorial policy.