Twist Bioscience (TWST)
Twist Bioscience on one page: short interest, daily short volume, fails to deliver, planned sales, large holders, 13F holders, financials, earnings dates and insider trades. Listed on Nasdaq, classified by the SEC as biological products, (no diagnostic substances).
10.2M
Short interest
settlement 2026-10-15
2.8
Days to cover
-1.0 days vs prior
57.6%
Short share of volume
2026-10-28
6
Fails to deliver
settlement 2026-09-28
Fri 13 Nov
Next earnings
estimated date
-$120.1M
Insider flow, 90 days
0 buys, 77 sells
As of 2026-10-28.
Short interest
FINRA, twice a month. The newest 48 settlements in the table, 48 in the chart. JSONAs of 15 October 2026, short interest in TWST is 10,207,499 shares, down 2,297,721 shares over the last month. Over the last 48 readings it ranged from 8,636,527 shares (31 January 2025) to 17,660,235 shares (15 June 2026). At the reported average volume of 3.6M shares a day that is 2.8 days to cover.
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| Settlement | Shares short | Change | Avg daily volume | Days to cover |
|---|---|---|---|---|
| 2026-10-15 | 10,207,499 | -3.4% | 3,616,960 | 2.82 |
| 2026-09-30 | 10,567,132 | -15.5% | 2,757,381 | 3.83 |
| 2026-09-15 | 12,505,220 | +3.6% | 1,401,252 | 8.92 |
| 2026-08-31 | 12,065,357 | -14.5% | 1,746,458 | 6.91 |
| 2026-08-14 | 14,109,131 | +0.2% | 1,784,873 | 7.90 |
| 2026-07-31 | 14,075,357 | -0.3% | 1,265,389 | 11.12 |
| 2026-07-15 | 14,116,574 | +1.2% | 1,457,241 | 9.69 |
| 2026-06-30 | 13,949,973 | -21.0% | 2,533,176 | 5.51 |
| 2026-06-15 | 17,660,235 | +18.5% | 1,843,532 | 9.58 |
| 2026-05-29 | 14,898,695 | -10.1% | 1,658,090 | 8.99 |
| 2026-05-15 | 16,578,578 | +19.1% | 1,594,221 | 10.40 |
| 2026-04-30 | 13,914,949 | -4.2% | 1,330,661 | 10.46 |
| 2026-04-15 | 14,522,121 | +2.6% | 1,153,230 | 12.59 |
| 2026-03-31 | 14,149,704 | +10.0% | 1,185,409 | 11.94 |
| 2026-03-13 | 12,863,285 | +1.1% | 918,078 | 14.01 |
| 2026-02-27 | 12,726,314 | -2.2% | 1,295,875 | 9.82 |
| 2026-02-13 | 13,006,730 | +6.9% | 1,780,627 | 7.30 |
| 2026-01-30 | 12,167,392 | -2.7% | 1,208,682 | 10.07 |
| 2026-01-15 | 12,504,532 | -12.3% | 1,381,682 | 9.05 |
| 2025-12-31 | 14,259,994 | +3.8% | 1,093,911 | 13.04 |
| 2025-12-15 | 13,742,759 | +7.8% | 1,179,611 | 11.65 |
| 2025-11-28 | 12,752,433 | +17.0% | 1,872,082 | 6.81 |
| 2025-11-14 | 10,898,965 | +3.3% | 1,851,190 | 5.89 |
| 2025-10-31 | 10,548,267 | -2.9% | 1,653,578 | 6.38 |
| 2025-10-15 | 10,860,765 | -16.4% | 2,022,934 | 5.37 |
| 2025-09-30 | 12,982,960 | +1.3% | 1,598,917 | 8.12 |
| 2025-09-15 | 12,816,246 | +25.2% | 1,625,092 | 7.89 |
| 2025-08-29 | 10,234,719 | -7.0% | 1,103,796 | 9.27 |
| 2025-08-15 | 11,008,222 | +5.5% | 2,622,206 | 4.20 |
| 2025-07-31 | 10,437,018 | -2.9% | 907,534 | 11.50 |
| 2025-07-15 | 10,745,056 | -2.6% | 899,046 | 11.95 |
| 2025-06-30 | 11,033,462 | +7.0% | 1,034,603 | 10.66 |
| 2025-06-13 | 10,308,992 | -3.5% | 1,233,128 | 8.36 |
| 2025-05-30 | 10,683,072 | +0.6% | 1,139,161 | 9.38 |
| 2025-05-15 | 10,616,307 | +6.6% | 1,348,010 | 7.88 |
| 2025-04-30 | 9,961,389 | +2.4% | 930,046 | 10.71 |
| 2025-04-15 | 9,726,318 | +1.4% | 1,637,627 | 5.94 |
| 2025-03-31 | 9,592,757 | +8.6% | 852,311 | 11.25 |
| 2025-03-14 | 8,830,123 | -5.0% | 1,436,284 | 6.15 |
| 2025-02-28 | 9,299,111 | +0.9% | 993,849 | 9.36 |
| 2025-02-14 | 9,215,413 | +6.7% | 1,052,599 | 8.75 |
| 2025-01-31 | 8,636,527 | -5.9% | 754,312 | 11.45 |
| 2025-01-15 | 9,175,202 | +5.5% | 684,059 | 13.41 |
| 2024-12-31 | 8,697,864 | -2.9% | 812,678 | 10.70 |
| 2024-12-13 | 8,953,899 | -7.2% | 755,262 | 11.86 |
| 2024-11-29 | 9,645,946 | +10.3% | 957,505 | 10.07 |
| 2024-11-15 | 8,747,935 | -3.0% | 955,201 | 9.16 |
| 2024-10-31 | 9,020,037 | +2.1% | 531,911 | 16.96 |
Daily short volume
FINRA Reg SHO, the last 30 sessions. JSONAs of 28 October 2026, the short share of TWST volume is 57.6%, up 5.4 points over the last five sessions. Over the last 30 readings it ranged from 31.4% (25 September 2026) to 62.6% (27 October 2026). The latest reading is 10.7 points above the 30-session average of 46.9%, on 1.7M shares reported.
| Date | Short volume | Total volume | Short share | Exempt |
|---|---|---|---|---|
| 2026-10-28 | 975K | 1.7M | 57.6% | 1,895 |
| 2026-10-27 | 479K | 765K | 62.6% | 7 |
| 2026-10-26 | 351K | 603K | 58.2% | 20 |
| 2026-10-23 | 436K | 761K | 57.3% | 18,164 |
| 2026-10-22 | 520K | 1.3M | 40.6% | 11,719 |
| 2026-10-21 | 584K | 1.1M | 52.1% | 53 |
| 2026-10-20 | 543K | 955K | 56.9% | 0 |
| 2026-10-19 | 352K | 572K | 61.5% | 0 |
| 2026-10-16 | 608K | 1.3M | 45.3% | 20,558 |
| 2026-10-15 | 630K | 1.6M | 39.6% | 14,015 |
| 2026-10-14 | 332K | 866K | 38.4% | 0 |
| 2026-10-13 | 220K | 672K | 32.7% | 515 |
| 2026-10-12 | 321K | 951K | 33.8% | 6,974 |
| 2026-10-09 | 638K | 1.5M | 41.6% | 0 |
| 2026-10-08 | 1.0M | 1.9M | 54.2% | 51 |
| 2026-10-07 | 936K | 2.3M | 40.9% | 61,095 |
| 2026-10-06 | 1.5M | 3.1M | 47.1% | 74,939 |
| 2026-10-05 | 597K | 1.2M | 49.0% | 1,085 |
| 2026-10-02 | 340K | 986K | 34.4% | 651 |
| 2026-10-01 | 609K | 1.2M | 49.9% | 875 |
| 2026-09-30 | 720K | 1.2M | 60.3% | 232 |
| 2026-09-29 | 494K | 1.1M | 46.7% | 106 |
| 2026-09-28 | 354K | 947K | 37.4% | 234 |
| 2026-09-25 | 437K | 1.4M | 31.4% | 312 |
| 2026-09-24 | 791K | 1.6M | 49.2% | 3,757 |
| 2026-09-23 | 456K | 1.0M | 43.9% | 1,459 |
| 2026-09-22 | 451K | 1.2M | 39.0% | 180 |
| 2026-09-21 | 487K | 1.2M | 41.8% | 165 |
| 2026-09-18 | 513K | 846K | 60.6% | 5,610 |
| 2026-09-17 | 691K | 1.7M | 41.6% | 1,084 |
Fails to deliver
SEC, the last 30 settlement dates with a fail. JSONAs of 28 September 2026, the fails-to-deliver balance in TWST is 6 shares, down 1 share over the last settlement date. Over the last 30 readings it ranged from 1 share (25 August 2026) to 172,839 shares (26 June 2026). The latest reading sits at the bottom of that range.
| Settlement | Shares failed | Price | Value |
|---|---|---|---|
| 2026-09-28 | 6 | $182.83 | $1K |
| 2026-09-25 | 7 | $184.03 | $1K |
| 2026-09-21 | 8,465 | $166.99 | $1.4M |
| 2026-09-18 | 80 | $155.56 | $12K |
| 2026-09-14 | 1,028 | $127.22 | $131K |
| 2026-09-03 | 6,650 | $131.00 | $871K |
| 2026-08-31 | 2,383 | $141.38 | $337K |
| 2026-08-28 | 602 | $153.10 | $92K |
| 2026-08-26 | 42 | $151.42 | $6K |
| 2026-08-25 | 1 | $140.80 | $141 |
| 2026-08-20 | 1,144 | $142.39 | $163K |
| 2026-08-19 | 29 | $116.10 | $3K |
| 2026-08-18 | 26,759 | $124.41 | $3.3M |
| 2026-08-17 | 2,921 | $118.57 | $346K |
| 2026-08-14 | 452 | $125.29 | $57K |
| 2026-08-10 | 11,941 | $115.67 | $1.4M |
| 2026-08-07 | 3 | $109.08 | $327 |
| 2026-08-06 | 1,352 | $115.01 | $155K |
| 2026-08-04 | 2,598 | $101.06 | $263K |
| 2026-07-24 | 6 | $92.44 | $555 |
| 2026-07-20 | 522 | $93.85 | $49K |
| 2026-07-17 | 2,578 | $91.23 | $235K |
| 2026-07-16 | 68 | $92.61 | $6K |
| 2026-07-14 | 412 | $90.35 | $37K |
| 2026-07-09 | 497 | $89.38 | $44K |
| 2026-07-08 | 1,268 | $91.03 | $115K |
| 2026-07-07 | 1,042 | $99.93 | $104K |
| 2026-07-06 | 718 | $99.24 | $71K |
| 2026-06-26 | 172,839 | $96.65 | $16.7M |
| 2026-06-25 | 365 | $91.35 | $33K |
Insider trades
SEC Form 4, newest first. JSONInsiders at TWST reported 77 open-market sells worth $120.1M in the last 90 days and no open-market buys. Latest filing: Finn Patrick John (President and COO) on 2026-10-23.
| Date | Insider | Title | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|---|
| 2026-10-23 | Finn Patrick John | President and COO | Sell | 2K | $134.59 | $302K | 183K |
| 2026-10-09 | Laponis Adam | Chief Financial Officer | Sell | 2K | $156.30 | $385K | 98K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 45 | $207.46 | $9K | 563K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 146 | $206.84 | $30K | 563K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 297 | $205.78 | $61K | 563K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 290 | $204.80 | $59K | 563K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 432 | $203.61 | $88K | 564K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 1K | $202.32 | $206K | 564K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 481 | $201.26 | $97K | 565K |
| 2026-10-05 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $200.44 | $369K | 565K |
| 2026-10-02 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 1K | $188.88 | $280K | 43K |
| 2026-10-02 | Leproust Emily M. | Chief Executive Officer | Sell | 46K | $188.88 | $8.6M | 567K |
| 2026-10-02 | Laponis Adam | Chief Financial Officer | Sell | 8K | $188.88 | $1.5M | 101K |
| 2026-10-02 | Green Paula | SVP of Human Resources | Sell | 10K | $188.88 | $1.9M | 107K |
| 2026-10-02 | Finn Patrick John | President and COO | Sell | 26K | $188.88 | $4.9M | 185K |
| 2026-10-02 | Cho Dennis | See Remarks | Sell | 10K | $188.88 | $1.8M | 64K |
| 2026-10-01 | Leproust Emily M. | Chief Executive Officer | Sell | 655 | $200.00 | $131K | 613K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 83 | $184.60 | $15K | 614K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 501 | $183.76 | $92K | 614K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 16 | $182.50 | $3K | 614K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 21 | $181.45 | $4K | 614K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 515 | $180.39 | $93K | 614K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 143 | $179.93 | $26K | 615K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 330 | $178.67 | $59K | 615K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 164 | $177.17 | $29K | 615K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 945 | $176.39 | $167K | 615K |
| 2026-09-24 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $175.23 | $435K | 616K |
| 2026-09-21 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $165.49 | $279K | 619K |
| 2026-09-21 | Green Paula | SVP of Human Resources | Sell | 294 | $165.49 | $49K | 117K |
| 2026-09-21 | Cho Dennis | See Remarks | Sell | 348 | $165.49 | $58K | 73K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 869 | $163.39 | $142K | 621K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 3K | $162.31 | $416K | 621K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 11K | $161.49 | $1.8M | 624K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 14K | $160.44 | $2.3M | 635K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 24K | $159.53 | $3.8M | 650K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 232K | $158.09 | $36.7M | 674K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 32K | $157.49 | $5.1M | 906K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 9K | $156.47 | $1.4M | 938K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 13K | $155.46 | $2.1M | 947K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 4K | $154.17 | $644K | 960K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 3K | $153.40 | $521K | 965K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 7K | $152.21 | $1.0M | 968K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $151.46 | $370K | 975K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Exercise or conversion | 75K | $8.82 | $665K | 977K |
| 2026-09-17 | Leproust Emily M. | Chief Executive Officer | Exercise or conversion | 133K | $26.66 | $3.6M | 902K |
| 2026-09-08 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 238 | $122.62 | $29K | 44K |
| 2026-09-08 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $122.62 | $282K | 768K |
| 2026-09-08 | Green Paula | SVP of Human Resources | Sell | 907 | $122.62 | $111K | 117K |
| 2026-09-08 | Cho Dennis | See Remarks | Sell | 412 | $122.62 | $51K | 74K |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sell | 1K | $154.45 | $169K | 771K |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sell | 9K | $153.93 | $1.4M | 772K |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sell | 6K | $152.75 | $979K | 781K |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sell | 12K | $151.35 | $1.9M | 787K |
| 2026-08-25 | Leproust Emily M. | Chief Executive Officer | Sell | 13K | $150.56 | $1.9M | 800K |
| 2026-08-24 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 854 | $140.77 | $120K | 45K |
| 2026-08-21 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 669 | $139.07 | $93K | 45K |
| 2026-08-21 | Leproust Emily M. | Chief Executive Officer | Sell | 7K | $139.07 | $923K | 812K |
| 2026-08-21 | Laponis Adam | Chief Financial Officer | Sell | 2K | $139.07 | $273K | 109K |
| 2026-08-21 | Green Paula | SVP of Human Resources | Sell | 1K | $139.07 | $189K | 118K |
| 2026-08-21 | Finn Patrick John | President and COO | Sell | 4K | $139.07 | $563K | 211K |
| 2026-08-21 | Cho Dennis | See Remarks | Sell | 2K | $139.07 | $222K | 74K |
| 2026-08-19 | Cho Dennis | See Remarks | Sell | 14K | $129.75 | $1.8M | 76K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 2K | $122.58 | $245K | 215K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 6K | $121.01 | $762K | 217K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 13K | $119.86 | $1.5M | 223K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 5K | $119.04 | $536K | 236K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 9K | $117.70 | $1.0M | 240K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 10K | $116.82 | $1.2M | 249K |
| 2026-08-18 | Finn Patrick John | President and COO | Sell | 33K | $115.90 | $3.9M | 260K |
| 2026-08-18 | Finn Patrick John | President and COO | Exercise or conversion | 23K | $67.85 | $1.6M | 293K |
| 2026-08-12 | Leproust Emily M. | Chief Executive Officer | Sell | 20K | $125.08 | $2.5M | 819K |
| 2026-08-12 | Leproust Emily M. | Chief Executive Officer | Exercise or conversion | 20K | $26.66 | $532K | 839K |
| 2026-08-12 | BLAKE KATRYN | Director | Sell | 2K | $122.88 | $275K | 17K |
| 2026-08-10 | Leproust Emily M. | Chief Executive Officer | Sell | 113K | $125.16 | $14.2M | 819K |
| 2026-08-10 | Leproust Emily M. | Chief Executive Officer | Exercise or conversion | 113K | $26.66 | $3.0M | 932K |
| 2026-08-07 | CHESS ROBERT | Director | Sell | 18K | $110.89 | $2.0M | 21K |
| 2026-08-07 | CHESS ROBERT | Director | Exercise or conversion | 18K | $11.89 | $219K | 40K |
| 2026-08-05 | Cho Dennis | See Remarks | Sell | 14K | $109.75 | $1.6M | 90K |
| 2026-08-03 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 167 | $85.32 | $14K | 46K |
| 2026-08-03 | Leproust Emily M. | Chief Executive Officer | Sell | 5K | $85.32 | $435K | 819K |
| 2026-08-03 | Green Paula | SVP of Human Resources | Sell | 1K | $85.32 | $97K | 119K |
| 2026-08-03 | Finn Patrick John | President and COO | Sell | 3K | $85.32 | $246K | 270K |
| 2026-08-03 | Cho Dennis | See Remarks | Sell | 1K | $85.32 | $91K | 104K |
| 2026-07-23 | Finn Patrick John | President and COO | Sell | 2K | $93.89 | $210K | 273K |
| 2026-07-09 | Laponis Adam | Chief Financial Officer | Sell | 2K | $94.33 | $226K | 110K |
| 2026-06-25 | Leproust Emily M. | Chief Executive Officer | Sell | 19K | $95.00 | $1.8M | 824K |
| 2026-06-24 | Cho Dennis | See Remarks | Sell | 14K | $89.75 | $1.3M | 105K |
| 2026-06-22 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $87.32 | $147K | 843K |
| 2026-06-22 | Cho Dennis | See Remarks | Sell | 346 | $87.32 | $30K | 119K |
| 2026-06-22 | Green Paula | SVP of Human Resources | Sell | 291 | $87.32 | $25K | 120K |
| 2026-06-15 | Green Paula | SVP of Human Resources | Sell | 24K | $81.62 | $2.0M | 123K |
| 2026-06-15 | Green Paula | SVP of Human Resources | Exercise or conversion | 26K | $23.33 | $610K | 147K |
| 2026-06-15 | Green Paula | SVP of Human Resources | Sell | 2K | $82.17 | $167K | 121K |
| 2026-06-08 | WERNER ROBERT F. | Chief Accounting Officer | Gift | 500 | $0.00 | $0 | 46K |
| 2026-06-08 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 1K | $69.07 | $78K | 47K |
| 2026-06-08 | WERNER ROBERT F. | Chief Accounting Officer | Sell | 232 | $69.84 | $16K | 48K |
| 2026-06-08 | Leproust Emily M. | Chief Executive Officer | Sell | 2K | $69.84 | $158K | 845K |
| 2026-06-08 | Green Paula | SVP of Human Resources | Sell | 884 | $69.84 | $62K | 121K |
| 2026-06-08 | Cho Dennis | See Remarks | Sell | 402 | $69.84 | $28K | 120K |
| 2026-05-29 | Laponis Adam | Chief Financial Officer | Sell | 4K | $70.00 | $280K | 113K |
Form 4 filings are due within two business days of the trade. Insiders sell for many reasons that say nothing about the company; open-market buys are rarer.
Planned sales (Form 144)
Newest first. JSON50 Form 144 notices on file for TWST worth $124.0M at the prices reported; 40 in the last 90 days worth $118.0M. Latest: Finn Patrick John filed on 2026-10-23 to sell 2,245 shares ($302K) from 2026-10-23.
| Filed | Seller | Shares | Market value | Of outstanding | Sale from | Broker |
|---|---|---|---|---|---|---|
| 2026-10-23 | Finn Patrick JohnOfficer | 2K | $302K | 0.004% | 2026-10-23 | Fidelity Brokerage Services LLC |
| 2026-10-09 | Laponis AdamOfficer | 2K | $385K | 0.004% | 2026-10-09 | Fidelity Brokerage Services LLC |
| 2026-10-05 | Leproust Emily M.Officer, Director | 5K | $919K | 0.007% | 2026-10-05 | Fidelity Brokerage Services LLC |
| 2026-10-02 | Laponis AdamOfficer | 8K | $1.5M | 0.013% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-02 | Leproust Emily M.Officer, Director | 46K | $8.6M | 0.073% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-02 | Cho DennisOfficer | 10K | $1.8M | 0.015% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-02 | WERNER ROBERT F.Officer | 1K | $280K | 0.002% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-02 | Green PaulaOfficer | 10K | $1.9M | 0.016% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-02 | Finn Patrick JohnOfficer | 26K | $4.9M | 0.041% | 2026-10-02 | Fidelity Brokerage Services LLC |
| 2026-10-01 | Leproust Emily M.Officer, Director | 655 | $131K | 0.001% | 2026-10-01 | Fidelity Brokerage Services LLC |
| 2026-09-24 | Leproust Emily M.Officer, Director | 5K | $923K | 0.008% | 2026-09-24 | Fidelity Brokerage Services LLC |
| 2026-09-21 | Cho DennisOfficer | 348 | $58K | 0.001% | 2026-09-21 | Fidelity Brokerage Services LLC |
| 2026-09-21 | Green PaulaOfficer | 294 | $49K | 0.000% | 2026-09-21 | Fidelity Brokerage Services LLC |
| 2026-09-21 | Leproust Emily M.Officer, Director | 2K | $279K | 0.003% | 2026-09-21 | Fidelity Brokerage Services LLC |
| 2026-09-17 | Leproust Emily M.Officer, Director | 62K | $9.3M | 0.098% | 2026-09-17 | Fidelity Brokerage Services LLC |
| 2026-09-17 | Leproust Emily M.Officer, Director | 295K | $44.7M | 0.470% | 2026-09-17 | Fidelity Brokerage Services LLC |
| 2026-09-08 | WERNER ROBERT F.Officer | 238 | $29K | 0.000% | 2026-09-08 | Fidelity Brokerage Services LLC |
| 2026-09-08 | Leproust Emily M.Officer, Director | 2K | $282K | 0.004% | 2026-09-08 | Fidelity Brokerage Services LLC |
| 2026-09-08 | Green PaulaOfficer | 907 | $111K | 0.001% | 2026-09-08 | Fidelity Brokerage Services LLC |
| 2026-09-08 | Cho DennisOfficer | 412 | $51K | 0.001% | 2026-09-08 | Fidelity Brokerage Services LLC |
| 2026-08-25 | Leproust Emily M.Officer, Director | 42K | $6.3M | 0.066% | 2026-08-25 | Fidelity Brokerage Services LLC |
| 2026-08-24 | WERNER ROBERT F.Officer | 854 | $120K | 0.001% | 2026-08-24 | Fidelity Brokerage Services LLC |
| 2026-08-21 | WERNER ROBERT F.Officer | 669 | $93K | 0.001% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-21 | Leproust Emily M.Officer, Director | 7K | $923K | 0.011% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-21 | Laponis AdamOfficer | 2K | $273K | 0.003% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-21 | Green PaulaOfficer | 1K | $189K | 0.002% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-21 | Finn Patrick JohnOfficer | 4K | $563K | 0.006% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-21 | Cho DennisOfficer | 2K | $222K | 0.003% | 2026-08-21 | Fidelity Brokerage Services LLC |
| 2026-08-19 | Cho DennisOfficer | 14K | $1.8M | 0.023% | 2026-08-19 | Fidelity Brokerage Services LLC |
| 2026-08-18 | Finn Patrick JohnOfficer | 78K | $9.5M | 0.125% | 2026-08-18 | Fidelity Brokerage Services LLC |
| 2026-08-12 | Leproust Emily M.Officer, Director | 20K | $2.5M | 0.032% | 2026-08-12 | Fidelity Brokerage Services LLC |
| 2026-08-12 | BLAKE KATRYNDirector | 2K | $275K | 0.004% | 2026-08-12 | Fidelity Brokerage Services LLC |
| 2026-08-10 | Leproust Emily M.Officer, Director | 113K | $14.2M | 0.181% | 2026-08-10 | Fidelity Brokerage Services LLC |
| 2026-08-07 | CHESS ROBERTDirector | 18K | $2.0M | 0.029% | 2026-08-07 | Fidelity Brokerage Services LLC |
| 2026-08-05 | Cho DennisOfficer | 14K | $1.6M | 0.023% | 2026-08-05 | Fidelity Brokerage Services LLC |
| 2026-08-03 | WERNER ROBERT F.Officer | 167 | $14K | 0.000% | 2026-08-03 | Fidelity Brokerage Services LLC |
| 2026-08-03 | Leproust Emily M.Officer, Director | 5K | $435K | 0.008% | 2026-08-03 | Fidelity Brokerage Services LLC |
| 2026-08-03 | Green PaulaOfficer | 1K | $97K | 0.002% | 2026-08-03 | Fidelity Brokerage Services LLC |
| 2026-08-03 | Finn Patrick JohnOfficer | 3K | $246K | 0.005% | 2026-08-03 | Fidelity Brokerage Services LLC |
| 2026-08-03 | Cho DennisOfficer | 1K | $91K | 0.002% | 2026-08-03 | Fidelity Brokerage Services LLC |
| 2026-07-23 | Finn Patrick JohnOfficer | 2K | $210K | 0.004% | 2026-07-23 | Fidelity Brokerage Services LLC |
| 2026-07-09 | Laponis AdamOfficer | 2K | $226K | 0.004% | 2026-07-09 | Fidelity Brokerage Services LLC |
| 2026-06-25 | Leproust Emily M.Officer, Director | 19K | $1.8M | 0.030% | 2026-06-25 | Fidelity Brokerage Services LLC |
| 2026-06-24 | Cho DennisOfficer | 14K | $1.3M | 0.023% | 2026-06-24 | Fidelity Brokerage Services LLC |
| 2026-06-22 | Leproust Emily M.Officer, Director | 2K | $147K | 0.003% | 2026-06-22 | Fidelity Brokerage Services LLC |
| 2026-06-22 | Green PaulaOfficer | 291 | $25K | 0.000% | 2026-06-22 | Fidelity Brokerage Services LLC |
| 2026-06-22 | Cho DennisOfficer | 346 | $30K | 0.001% | 2026-06-22 | Fidelity Brokerage Services LLC |
| 2026-06-15 | Green PaulaOfficer | 26K | $2.1M | 0.042% | 2026-06-15 | Fidelity Brokerage Services LLC |
| 2026-06-08 | WERNER ROBERT F.Officer | 1K | $78K | 0.002% | 2026-06-08 | Fidelity Brokerage Services LLC |
| 2026-06-08 | WERNER ROBERT F.Officer | 232 | $16K | 0.000% | 2026-06-08 | Fidelity Brokerage Services LLC |
Large holders (13D and 13G)
One row per reporting person with its latest filing, newest first. JSON11 holders report 5% or more of TWST in their latest filing, all on Schedule 13G (passive). The largest reported stake is FMR LLC at 13.2% of the class (8,760,081 shares), filed 2026-09-08 for an event on 2026-08-31.
| Filed | Form | Holder | Shares | Of class | Event |
|---|---|---|---|---|---|
| 2026-09-08 | 13G/Ano. 10 | ARK Investment Management LLCinvestment adviser | 3.4M | 5.1% | 2026-08-31 |
| 2026-09-08 | 13G/Ano. 10 | Catherine D. Woodparent holding company, individual | 3.4M | 5.1% | 2026-08-31 |
| 2026-09-08 | 13G/Ano. 1 | FMR LLCparent holding company | 8.8M | 13.2% | 2026-08-31 |
| 2026-09-08 | 13G/Ano. 1 | Abigail P. Johnsonindividual | 8.8M | 13.2% | 2026-08-31 |
| 2026-08-14 | 13G/Ano. 2 | EdgePoint Investment Group Inc.investment adviser, non-US institution | 2.5M | 4.2% | 2026-06-30 |
| 2026-08-14 | 13G | T. Rowe Price Associates, Inc.investment adviser | 3.6M | 5.8% | 2026-06-30 |
| 2026-08-13 | 13G/Ano. 6 | Artisan Partners Asset Management Inc.parent holding company | 4.8M | 7.7% | 2026-06-30 |
| 2026-08-13 | 13G/Ano. 6 | Artisan Partners Holdings LPparent holding company | 4.8M | 7.7% | 2026-06-30 |
| 2026-08-13 | 13G/Ano. 6 | Artisan Investments GP LLCparent holding company | 4.8M | 7.7% | 2026-06-30 |
| 2026-08-13 | 13G/Ano. 6 | Artisan Partners Limited Partnershipinvestment adviser | 4.8M | 7.7% | 2026-06-30 |
| 2026-08-11 | 13G/Ano. 3 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLCinvestment adviser | 2.2M | 3.5% | 2026-06-30 |
| 2026-04-30 | 13G | Vanguard Capital Managementinvestment adviser | 3.1M | 5.0% | 2026-03-31 |
| 2026-03-27 | 13G/Ano. 5 | The Vanguard Groupinvestment adviser | 0 | 0.0% | 2026-03-13 |
| 2025-11-10 | 13G | STATE STREET CORPORATIONparent holding company | 3.1M | 5.1% | 2025-09-30 |
13F holders
Tracked managers holding TWST at their latest 13F. JSON7 of the 30 tracked managers held TWST at their latest 13F, $739.4M in total at quarter-end prices. ARK Investment Management is the largest at $468.1M (3.0% of its portfolio) as of 2026-06-30. Over the prior quarter 4 added shares and 3 cut.
| Fund | Quarter | Shares | Value | Of portfolio | Change in shares |
|---|---|---|---|---|---|
| ARK Investment Management | 2026-06-30 | 4.5M | $468.1M | 3.04% | -1.8M |
| D. E. Shaw & Co. | 2026-06-30 | 1.2M | $122.0M | 0.06% | +1.1M |
| Citadel Advisors | 2026-06-30 | 862K | $88.7M | 0.01% | -358K |
| Millennium Management | 2026-06-30 | 347K | $35.7M | 0.01% | -3K |
| AQR Capital Management | 2026-06-30 | 129K | $13.3M | 0.00% | +5K |
| Two Sigma Investments | 2026-06-30 | 95K | $9.7M | 0.01% | +57K |
| Bridgewater Associates | 2026-06-30 | 19K | $1.9M | 0.01% | new |
Only the 30 tracked managers on the funds hub; a 13F reports long positions in US listed stock at quarter end, 45 days late, and says nothing about shorts or positions sold since.
Financials
SEC XBRL, as filed. JSONIn FY 2025 it generated -$47.6M of operating cash flow.
- Cash
- $117.4M
- Equity
- $445.7M
- Total assets
- $672.4M
- Shares outstanding
- 62,707,424
Quarterly, last 8 quarters
| Quarter | Period end | Revenue | Net income | Margin | Diluted EPS |
|---|---|---|---|---|---|
| Q3 FY 2026 | 2026-06-30 | n/a | -$35.1M | n/a | -0.56 |
| Q2 FY 2026 | 2026-03-31 | n/a | -$44.0M | n/a | -0.71 |
| Q1 FY 2026 | 2025-12-31 | n/a | -$30.5M | n/a | -0.50 |
| Q4 FY 2025derived | 2025-09-30 | n/a | -$27.1M | n/a | n/a |
| Q3 FY 2025 | 2025-06-30 | n/a | $20.4M | n/a | 0.33 |
| Q2 FY 2025 | 2025-03-31 | n/a | -$39.3M | n/a | -0.66 |
| Q1 FY 2025 | 2024-12-31 | n/a | -$31.6M | n/a | -0.53 |
| Q4 FY 2024derived | 2024-09-30 | n/a | -$34.7M | n/a | n/a |
Fiscal years, with buybacks and dividends
| Fiscal year | Ends | Revenue | Net income | Operating cash flow | Capex | Buybacks | Dividends |
|---|---|---|---|---|---|---|---|
| FY 2025 | 2025-09-30 | n/a | -$77.7M | -$47.6M | $28.0M | n/a | n/a |
| FY 2024 | 2024-09-30 | n/a | -$208.7M | -$64.1M | $5.1M | n/a | n/a |
| FY 2023 | 2023-09-30 | n/a | -$204.6M | -$142.5M | $27.8M | n/a | n/a |
| FY 2022 | 2022-09-30 | n/a | -$217.9M | -$124.4M | $101.9M | n/a | n/a |
| FY 2021 | 2021-09-30 | n/a | -$152.1M | -$112.2M | $27.1M | n/a | n/a |
Quarters are the three-month figures the company reports; a fourth quarter marked derived is the fiscal year less the three reported quarters, since companies report it only inside the 10-K. Fiscal years are the annual figures. Buybacks are the cash the company paid to repurchase its common stock in the year, not the amount authorized. Balance sheet lines are as of 2026-06-30; shares outstanding as of 2026-07-29 from the cover page.
What this page is
Twist Bioscience in the regulatory record
Regulators publish company data in separate files that never sit next to each other: FINRA's twice-monthly short interest, its daily short sale volume, the SEC's fails-to-deliver counts, and each insider's Form 4. A company page puts those series for one ticker on one URL, with planned sales, large holders, 13F holders and financials beside them, so the short position, the daily flow, the settlement fails and what insiders are doing can be read together.
Each section has its own history table, a one-line summary of the latest figures and its own JSON and CSV links, and says when its source last updated.
This page follows Twist Bioscience (TWST), SEC CIK 1581280, listed on Nasdaq, classified by the SEC as biological products, (no diagnostic substances). The cross-market tables live on the short interest and insider transactions hubs.
Source and updates
- Short interest
- FINRA consolidated short interestSource: FINRA.Twice a month, about eight business days after settlement. Latest 2026-10-15.JSON and CSV
- Daily short volume
- FINRA Reg SHO daily filesSource: FINRA.Every trading day, the morning after FINRA posts it. Latest 2026-10-28.JSON and CSV
- Fails to deliver
- SEC fails-to-deliver dataSource: SEC.Twice a month, a few weeks after the half month ends. Latest 2026-09-28.JSON and CSV
- Planned sales
- SEC EDGAR Form 144Source: SEC.New notices appear shortly after the SEC posts them; a notice is filed on or before the sale. Latest 2026-10-23.JSON and CSV
- Large holders
- SEC EDGAR Schedule 13D and 13GSource: SEC.New filings appear shortly after the SEC posts them. A 13D is due within five business days of crossing 5%; a 13G follows the passive schedule. Latest 2026-09-08.JSON and CSV
- 13F holders
- SEC EDGAR Form 13F-HRSource: SEC.Quarterly, filed within 45 days of quarter end; 30 tracked managers. Latest 2026-06-30.JSON and CSV
- Financials
- SEC EDGAR 10-K and 10-Q filingsSource: SEC.Weekly; values are as filed in the 10-Q and 10-K. Latest 2026-06-30.JSON and CSV
- Earnings dates
- SEC EDGAR 8-K filings (Item 2.02)Source: SEC.Twice a day. Reported dates come from the company's 8-K filings; the next date is marked as an estimate until the 8-K arrives. Latest 2026-08-03.JSON and CSV
- Insider trades
- SEC EDGAR Form 4Source: SEC.New filings appear shortly after the SEC posts them; they're due two business days after the trade. Latest 2026-10-23.JSON and CSV
- Company record
- EDGAR filing index for CIK 1581280Ticker, name and exchange from the SEC's company list, refreshed weekly.
- Rate limits
- 10 requests a minute without a key, 30 with a free key from a free account.
How to read it
- Read the position against the flow: rising short interest with a high daily short share is new shorting; rising short interest with a normal short share is old shorts holding on.
- Insider buys next to a large short position are rare and stand out; insider sells next to one are common and mean little.
- Fails to deliver matter relative to the float, not in absolute shares; a million failed shares in a mega cap is noise.
Analysis of what the data shows, not advice. XOOMAR does not recommend buying, selling or holding anything.
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Datasets
Frequently Asked Questions
How much of TWST is sold short?
10,207,499 shares were held short at the 2026-10-15 settlement, 2.8 days of average volume. FINRA publishes the next count about eight business days after the 15th and the last business day of the month.
What is TWST's daily short volume?
On 2026-10-28, 974,525 of the 1,693,253 TWST shares reported to FINRA were sold short, 57.6% of the day's reported volume. Short volume is a flow for one day, not a position.
Does TWST have fails to deliver?
The SEC's latest file shows 6 TWST shares failed to deliver at settlement 2026-09-28. Fails are reported per settlement date and published twice a month with a lag.
Are TWST insiders buying or selling?
Insiders at TWST reported 77 open-market sells worth $120.1M in the last 90 days and no open-market buys. Latest filing: Finn Patrick John (President and COO) on 2026-10-23.
Have TWST insiders filed to sell?
50 Form 144 notices on file for TWST worth $124.0M at the prices reported; 40 in the last 90 days worth $118.0M. Latest: Finn Patrick John filed on 2026-10-23 to sell 2,245 shares ($302K) from 2026-10-23.
Who owns 5% or more of TWST?
11 holders report 5% or more of TWST in their latest filing, all on Schedule 13G (passive). The largest reported stake is FMR LLC at 13.2% of the class (8,760,081 shares), filed 2026-09-08 for an event on 2026-08-31.
What did TWST report last quarter?
In FY 2025 it generated -$47.6M of operating cash flow.
Which tracked 13F managers own TWST?
7 of the 30 tracked 13F managers held TWST shares at their latest filing, $739.4M in all. The largest: Cathie Wood's ARK Investment Management (4.5M shares, $468.1M), D. E. Shaw & Co. (1.2M shares, $122.0M), Ken Griffin's Citadel Advisors (862K shares, $88.7M), Izzy Englander's Millennium Management (347K shares, $35.7M), Cliff Asness's AQR Capital Management (129K shares, $13.3M), Two Sigma Investments (95K shares, $9.7M). The table above lists all 7.
Data on this page is provided for informational purposes only and is not financial advice. See our editorial policy.