XOOMAR

Annovis Bio (ANVS)

Annovis Bio on one page: short interest, daily short volume, fails to deliver, planned sales, large holders, 13F holders, earnings dates and insider trades. Listed on NYSE, classified by the SEC as pharmaceutical preparations.

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5.7M

Short interest

settlement 2026-10-15

8.3

Days to cover

+2.4 days vs prior

56.0%

Short share of volume

2026-11-02

18,312

Fails to deliver

settlement 2026-10-14

Thu 12 Nov

Next earnings

estimated date

$0

Insider flow, 90 days

0 buys, 0 sells

As of 2026-11-02.

Short interest

FINRA, twice a month. The newest 48 settlements in the table, 48 in the chart. JSON

As of 15 October 2026, short interest in ANVS is 5,720,877 shares, down 301,163 shares over the last month. Over the last 48 readings it ranged from 1,032,901 shares (31 October 2025) to 6,022,040 shares (15 September 2026). The latest reading sits at the top of that range. At the reported average volume of 686K shares a day that is 8.3 days to cover.

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SettlementShares shortChangeAvg daily volumeDays to cover
2026-10-155,720,877-3.0%686,1578.34
2026-09-305,895,922-2.1%990,5735.95
2026-09-156,022,040+20.7%1,889,9183.19
2026-08-314,989,785+0.5%520,4059.59
2026-08-144,964,649-4.4%608,1318.16
2026-07-315,193,076-4.7%549,6849.45
2026-07-155,450,385+12.1%1,079,4705.05
2026-06-304,864,454+1.2%908,3205.36
2026-06-154,804,638-4.3%1,188,7654.04
2026-05-295,021,073+7.4%1,602,9983.13
2026-05-154,674,614-3.0%964,6194.85
2026-04-304,816,770+1.2%970,7354.96
2026-04-154,760,673+47.2%1,824,6572.61
2026-03-313,234,406+16.4%521,9466.20
2026-03-132,778,124+1.2%290,2169.57
2026-02-272,745,085-3.1%376,4607.29
2026-02-132,833,149-3.5%339,9808.33
2026-01-302,935,736-6.3%535,0905.49
2026-01-153,133,837+3.0%571,7495.48
2025-12-313,044,065+6.5%459,6506.62
2025-12-152,858,006+1.0%1,054,4222.71
2025-11-282,829,273+115.2%7,715,6241.00
2025-11-141,314,516+27.3%434,6803.02
2025-10-311,032,901-20.4%695,4521.49
2025-10-151,298,376-7.1%1,903,9931.00
2025-09-301,398,175-11.9%207,9386.72
2025-09-151,587,655-7.1%180,7188.79
2025-08-291,708,692-8.5%241,5417.07
2025-08-151,867,787-14.6%243,4547.67
2025-07-312,187,682-11.1%328,2266.67
2025-07-152,460,828+4.3%337,8607.28
2025-06-302,360,022+7.0%532,8404.43
2025-06-132,205,405+4.3%702,9413.14
2025-05-302,113,449+7.8%516,6074.09
2025-05-151,959,704+0.4%349,9495.60
2025-04-301,952,592+11.9%651,4273.00
2025-04-151,744,449-13.6%212,3088.22
2025-03-312,019,332+7.5%291,0126.94
2025-03-141,879,232+12.2%260,7497.21
2025-02-281,675,108+16.0%615,2572.72
2025-02-141,443,813-25.0%1,044,5771.38
2025-01-311,925,112-10.3%208,5919.23
2025-01-152,146,224+31.5%725,1932.96
2024-12-311,632,310+4.5%311,5995.24
2024-12-131,561,942+19.1%356,8504.38
2024-11-291,311,926-5.9%192,2936.82
2024-11-151,393,625-0.4%227,1466.14
2024-10-311,399,763+3.0%361,0213.88

Daily short volume

FINRA Reg SHO, the last 30 sessions. JSON

As of 2 November 2026, the short share of ANVS volume is 56.0%, down 6.1 points over the last five sessions. Over the last 30 readings it ranged from 35.5% (27 October 2026) to 78.5% (23 September 2026). The latest reading is 5.5 points below the 30-session average of 61.5%, on 2.0M shares reported.

DateShort volumeTotal volumeShort shareExempt
2026-11-021.1M2.0M56.0%21,389
2026-10-30758K1.0M73.8%14,933
2026-10-29839K1.2M69.9%1,151
2026-10-28407K674K60.4%25
2026-10-27247K696K35.5%0
2026-10-26158K254K62.1%1,880
2026-10-23109K183K59.4%1,000
2026-10-22186K284K65.4%0
2026-10-21155K247K63.0%0
2026-10-20231K456K50.5%30
2026-10-19181K365K49.4%980
2026-10-16200K326K61.4%1,802
2026-10-15185K351K52.6%174
2026-10-14207K440K47.0%402
2026-10-13372K530K70.2%0
2026-10-12178K260K68.4%0
2026-10-09155K235K65.8%0
2026-10-08180K322K55.9%0
2026-10-07172K226K76.2%0
2026-10-06254K335K75.9%300
2026-10-05135K363K37.1%0
2026-10-02230K348K66.3%0
2026-10-01282K639K44.1%0
2026-09-30245K326K75.1%3,600
2026-09-29244K381K64.1%0
2026-09-28424K719K58.9%2,589
2026-09-25135K260K52.0%0
2026-09-24344K480K71.8%0
2026-09-23469K598K78.5%250
2026-09-22456K586K77.8%0

Fails to deliver

SEC, the last 30 settlement dates with a fail. JSON

As of 14 October 2026, the fails-to-deliver balance in ANVS is 18,312 shares, up 2,885 shares over the last settlement date. Over the last 30 readings it ranged from 6 shares (12 August 2026) to 33,649 shares (11 September 2026).

SettlementShares failedPriceValue
2026-10-1418,312$1.06$19K
2026-10-1315,427$1.15$18K
2026-10-0910,981$1.17$13K
2026-10-0511,943$1.18$14K
2026-10-028,988$1.17$11K
2026-10-0113,799$1.27$18K
2026-09-305,629$1.30$7K
2026-09-2912,817$1.38$18K
2026-09-2810,005$1.31$13K
2026-09-259,979$1.33$13K
2026-09-245,823$1.27$7K
2026-09-171,021$1.04$1K
2026-09-1133,649$1.19$40K
2026-09-103,917$1.22$5K
2026-09-089,440$1.39$13K
2026-09-045,470$1.38$8K
2026-09-023,416$1.69$6K
2026-09-0113,409$1.72$23K
2026-08-2636$1.82$66
2026-08-2012,967$1.85$24K
2026-08-126$1.89$11
2026-08-0768$1.86$126
2026-07-214,906$1.69$8K
2026-07-07528$1.97$1K
2026-07-06744$1.93$1K
2026-07-01597$1.86$1K
2026-06-30600$1.86$1K
2026-06-2613,239$1.65$22K
2026-06-253,185$1.70$5K
2026-06-173,337$1.79$6K

Insider trades

SEC Form 4, newest first. JSON

No open-market insider trades were reported for ANVS in the last 90 days. The most recent filings are listed below. Latest filing: Hoffman Michael B (Director) on 2026-05-20.

DateInsiderTitleTypeSharesPriceValueOwned after
2026-05-20Hoffman Michael BDirectorBuy55K$1.90$104K3.4M
2026-05-20Hoffman Michael BDirectorBuy19K$1.80$34K3.3M
2026-05-20Hoffman Michael BDirectorBuy3K$1.75$4K3.3M
2026-04-02Hoffman Michael BDirectorBuy714K$2.10$1.5M3.3M
2025-12-08Hoffman Michael BDirectorBuy15K$4.24$64K2.6M
2025-12-08Hoffman Michael BDirectorBuy30K$4.34$130K2.6M
2025-11-24Hoffman Michael BDirectorBuy9K$3.85$35K2.5M
2025-11-24Hoffman Michael BDirectorBuy415$4.14$2K2.5M
2025-11-24Hoffman Michael BDirectorBuy28K$4.15$117K2.5M
2025-11-24Hoffman Michael BDirectorBuy1K$4.13$6K2.5M
2025-11-24Hoffman Michael BDirectorBuy28K$4.15$117K2.5M
2025-11-24Hoffman Michael BDirectorBuy415$4.14$2K2.5M
2025-11-24Hoffman Michael BDirectorBuy9K$3.85$35K2.5M
2025-11-24Hoffman Michael BDirectorBuy1K$4.13$6K2.5M
2025-11-21Hoffman Michael BDirectorBuy10K$3.50$35K2.5M
2025-11-21Hoffman Michael BDirectorBuy10K$3.49$35K2.5M
2025-11-14Hoffman Michael BDirectorBuy15K$2.11$32K2.5M
2025-10-28Maccecchini Maria-LuisaPresident & CEOBuy98K$2.05$200K1.2M
2025-10-28Hoffman Michael BDirectorBuy976K$2.05$2.0M2.5M
2025-09-10Bruck ClaudineDirectorExercise or conversion7K$0.14$100014K
2025-08-29Hoffman Michael BDirectorGrant5K$2.30$12K1.5M
2025-08-29Hoffman Michael BDirectorGrant5K$2.29$11K1.5M
2025-08-29Hoffman Michael BDirectorGrant5K$2.28$11K1.5M
2025-08-19Hoffman Michael BDirectorGrant1K$2.57$3K1.5M
2025-08-19Hoffman Michael BDirectorGrant6K$2.58$14K1.5M
2025-08-19Hoffman Michael BDirectorGrant5K$2.59$14K1.5M
2025-08-19Hoffman Michael BDirectorGrant7K$2.60$17K1.5M
2025-06-16Walsh AndrewVice President, FinanceGrant500$2.90$1K500
2025-06-13Hoffman Michael BDirectorGrant1$2.83$31.4M
2025-06-13Hoffman Michael BDirectorGrant25K$2.80$70K1.4M
2025-06-10McCarthy ReidDirectorGrant2K$2.95$6K9K
2025-06-04Maccecchini Maria-LuisaPresident & CEOGrant46K$3.37$155K1.1M
2025-05-29Hoffman Michael BDirectorGrant5K$2.43$12K1.4M
2024-03-31Maccecchini Maria-LuisaPresident and CEOGift10K$0.00$01.1M
2024-03-31Maccecchini Maria-LuisaPresident and CEOGift10K$0.00$01.1M
2024-03-28Maccecchini Maria-LuisaPresident and CEOGift10K$0.00$01.1M
2023-11-20Bruck ClaudineDirectorGrant1K$6.07$6K8K
2023-11-20Hagopian Henry IIIChief Financial OfficerGrant824$6.07$5K2K
2023-11-20Maccecchini Maria-LuisaPresident and CEOGrant41K$6.07$250K1.1M
2023-11-20White Mark K.DirectorGrant2K$6.07$12K61K
2023-11-20Hoffman Michael BDirector,TenPercentOwnerGrant165K$6.07$1.0M224K
2023-11-20McCarthy ReidDirectorGrant824$6.07$5K8K
2023-11-20Bruck ClaudineDirectorOther transaction0$0.00$07K
2023-11-20Hagopian Henry IIIChief Financial OfficerGrant820$6.10$5K2K
2023-11-20Maccecchini Maria-LuisaPresident and CEOGrant41K$6.10$250K1.1M
2023-11-20Hoffman Michael BDirector,TenPercentOwnerGrant164K$6.10$1000K223K
2023-11-20McCarthy ReidDirectorOther transaction0$0.00$07K
2023-11-20White Mark K.DirectorGrant2K$6.10$12K61K
2023-04-24Maccecchini Maria-LuisaPresident and CEOGift3K$0.00$01.1M
2023-04-07Maccecchini Maria-LuisaPresident and CEOGrant20K$12.61$252K1.1M
2023-04-07McCarthy ReidDirectorGrant476$12.61$6K7K
2023-04-07Hoffman Michael BDirector,TenPercentOwnerGrant59K$12.61$750K59K
2023-04-07Hagopian Henry IIIChief Financial OfficerGrant1K$12.61$13K1K
2023-04-07Bruck ClaudineDirectorGrant500$12.61$6K7K
2023-04-07White Mark K.DirectorGrant3K$12.61$38K59K
2023-02-06Maccecchini Maria-LuisaPresident and CEOExercise or conversion53K$0.14$7K1.0M
2022-01-14Maccecchini Maria-LuisaPresident and CEOExercise or conversion33K$0.14$5K988K
2022-01-04Hoffman Michael BDirector,TenPercentOwnerExercise or conversion30K$4.39$132K1.4M
2022-01-04Hoffman Michael BDirector,TenPercentOwnerTax withholding7K$19.78$132K1.4M
2022-01-04Hoffman Michael BDirector,TenPercentOwnerExercise or conversion7K$0.25$2K1.4M
2022-01-04Hoffman Michael BDirector,TenPercentOwnerTax withholding90$19.78$2K1.4M
2021-10-12White Mark K.DirectorBuy5K$27.40$137K56K
2021-10-11Maccecchini Maria-LuisaPRESIDENT AND CEOBuy18K$27.61$497K977K
2021-10-11Bruck ClaudineDirectorBuy181$27.66$5K6K
2021-08-19McCarthy ReidDirectorBuy500$37.61$19K7K
2020-02-03McGroarty Jeffrey BrianChief Financial OfficerBuy19K$7.15$138K53K
2020-02-03McGroarty Jeffrey BrianChief Financial OfficerBuy164$7.17$1K53K
2020-01-31White Mark K.DirectorConversion12Kprice not stated in the filingnot stated13K
2020-01-31White Mark K.DirectorBuy2K$6.00$10K2K
2020-01-31White Mark K.DirectorConversion35Kprice not stated in the filingnot stated48K
2020-01-31White Mark K.DirectorConversion3K$4.80$16K51K
2020-01-31McGroarty Jeffrey BrianChief Financial OfficerBuy33K$6.00$200K33K
2020-01-31Maccecchini Maria-LuisaPresident and CEOConversion8Kprice not stated in the filingnot stated216K
2020-01-31Maccecchini Maria-LuisaPresident and CEOBuy2K$6.00$10K208K
2020-01-31Maccecchini Maria-LuisaPresident and CEOConversion763Kprice not stated in the filingnot stated979K
2020-01-31Bruck ClaudineDirectorConversion4Kprice not stated in the filingnot stated5K
2020-01-31Bruck ClaudineDirectorConversion1K$4.80$5K6K
2020-01-31Bruck ClaudineDirectorBuy800$6.00$5K800
2020-01-31Whelan, Jr. Robert M.DirectorConversion11K$4.80$54K96K
2020-01-31Whelan, Jr. Robert M.DirectorConversion60Kprice not stated in the filingnot stated85K
2020-01-31Whelan, Jr. Robert M.DirectorBuy25K$6.00$150K25K
2020-01-31Hoffman Michael BDirector,TenPercentOwnerBuy33K$6.00$200K48K
2020-01-31Hoffman Michael BDirector,TenPercentOwnerConversion159Kprice not stated in the filingnot stated206K
2020-01-31Hoffman Michael BDirector,TenPercentOwnerConversion1.1Mprice not stated in the filingnot stated1.3M
2020-01-31Hoffman Michael BDirector,TenPercentOwnerConversion56K$4.80$268K1.4M

Form 4 filings are due within two business days of the trade. Insiders sell for many reasons that say nothing about the company; open-market buys are rarer.

Planned sales (Form 144)

Newest first. JSON

1 Form 144 notice on file for ANVS worth $15K at the prices reported; 0 in the last 90 days worth $0. Latest: White Mark K. filed on 2026-04-02 to sell 7,142 shares ($15K) from 2026-04-02.

FiledSellerSharesMarket valueOf outstandingSale fromBroker
2026-04-02White Mark K.Director7K$15K0.025%2026-04-02Stifel Nicolaus & Company Inc

Large holders (13D and 13G)

One row per reporting person with its latest filing, newest first. JSON

1 holder reports 5% or more of ANVS in its latest filing, on Schedule 13G (passive). The holder is Highbridge Capital Management, LLC at 6.1% of the class (2,775,578 shares), filed 2026-08-14 for an event on 2026-06-30.

FiledFormHolderSharesOf classEvent
2026-10-1513G/Ano. 1Ryan M. Laneparent holding company, individual2.2M5.0%2026-09-30
2026-10-1513G/Ano. 1Empery Asset Management, LPinvestment adviser, partnership2.2M5.0%2026-09-30
2026-08-1413GHighbridge Capital Management, LLCinvestment adviser, other entity2.8M6.1%2026-06-30

13F holders

Tracked managers holding ANVS at their latest 13F. JSON

4 of the 30 tracked managers held ANVS at their latest 13F, $3.4M in total at quarter-end prices. Renaissance Technologies is the largest at $1.9M (0.0% of its portfolio) as of 2026-06-30. Over the prior quarter 3 added shares and 1 cut.

FundQuarterSharesValueOf portfolioChange in shares
Renaissance Technologies2026-06-301.0M$1.9M0.00%+655K
Two Sigma Investments2026-06-30580K$1.1M0.00%-48K
Citadel Advisors2026-06-30244K$453K0.00%new
Millennium Management2026-06-3023K$44K0.00%new

Only the 30 tracked managers on the funds hub; a 13F reports long positions in US listed stock at quarter end, 45 days late, and says nothing about shorts or positions sold since.

What this page is

Annovis Bio in the regulatory record

Regulators publish company data in separate files that never sit next to each other: FINRA's twice-monthly short interest, its daily short sale volume, the SEC's fails-to-deliver counts, and each insider's Form 4. A company page puts those series for one ticker on one URL, with planned sales, large holders, 13F holders and financials beside them, so the short position, the daily flow, the settlement fails and what insiders are doing can be read together.

Each section has its own history table, a one-line summary of the latest figures and its own JSON and CSV links, and says when its source last updated.

This page follows Annovis Bio (ANVS), SEC CIK 1477845, listed on NYSE, classified by the SEC as pharmaceutical preparations. The cross-market tables live on the short interest and insider transactions hubs.

Source and updates

Short interest
FINRA consolidated short interestSource: FINRA.Twice a month, about eight business days after settlement. Latest 2026-10-15.JSON and CSV
Daily short volume
FINRA Reg SHO daily filesSource: FINRA.Every trading day, the morning after FINRA posts it. Latest 2026-11-02.JSON and CSV
Fails to deliver
SEC fails-to-deliver dataSource: SEC.Twice a month, a few weeks after the half month ends. Latest 2026-10-14.JSON and CSV
Planned sales
SEC EDGAR Form 144Source: SEC.New notices appear shortly after the SEC posts them; a notice is filed on or before the sale. Latest 2026-04-02.JSON and CSV
Large holders
SEC EDGAR Schedule 13D and 13GSource: SEC.New filings appear shortly after the SEC posts them. A 13D is due within five business days of crossing 5%; a 13G follows the passive schedule. Latest 2026-10-15.JSON and CSV
13F holders
SEC EDGAR Form 13F-HRSource: SEC.Quarterly, filed within 45 days of quarter end; 30 tracked managers. Latest 2026-06-30.JSON and CSV
Earnings dates
SEC EDGAR 8-K filings (Item 2.02)Source: SEC.Twice a day. Reported dates come from the company's 8-K filings; the next date is marked as an estimate until the 8-K arrives. Latest 2026-08-14.JSON and CSV
Insider trades
SEC EDGAR Form 4Source: SEC.New filings appear shortly after the SEC posts them; they're due two business days after the trade. Latest 2026-05-20.JSON and CSV
Company record
EDGAR filing index for CIK 1477845Ticker, name and exchange from the SEC's company list, refreshed weekly.
Rate limits
10 requests a minute without a key, 30 with a free key from a free account.

How to read it

  • Read the position against the flow: rising short interest with a high daily short share is new shorting; rising short interest with a normal short share is old shorts holding on.
  • Insider buys next to a large short position are rare and stand out; insider sells next to one are common and mean little.
  • Fails to deliver matter relative to the float, not in absolute shares; a million failed shares in a mega cap is noise.

Analysis of what the data shows, not advice. XOOMAR does not recommend buying, selling or holding anything.

Datasets

Frequently Asked Questions

How much of ANVS is sold short?
5,720,877 shares were held short at the 2026-10-15 settlement, 8.3 days of average volume. FINRA publishes the next count about eight business days after the 15th and the last business day of the month.
What is ANVS's daily short volume?
On 2026-11-02, 1,123,871 of the 2,007,893 ANVS shares reported to FINRA were sold short, 56.0% of the day's reported volume. Short volume is a flow for one day, not a position.
Does ANVS have fails to deliver?
The SEC's latest file shows 18,312 ANVS shares failed to deliver at settlement 2026-10-14. Fails are reported per settlement date and published twice a month with a lag.
Are ANVS insiders buying or selling?
No open-market insider trades were reported for ANVS in the last 90 days. The most recent filings are listed below. Latest filing: Hoffman Michael B (Director) on 2026-05-20.
Have ANVS insiders filed to sell?
1 Form 144 notice on file for ANVS worth $15K at the prices reported; 0 in the last 90 days worth $0. Latest: White Mark K. filed on 2026-04-02 to sell 7,142 shares ($15K) from 2026-04-02.
Who owns 5% or more of ANVS?
1 holder reports 5% or more of ANVS in its latest filing, on Schedule 13G (passive). The holder is Highbridge Capital Management, LLC at 6.1% of the class (2,775,578 shares), filed 2026-08-14 for an event on 2026-06-30.
Which tracked 13F managers own ANVS?
4 of the 30 tracked 13F managers held ANVS shares at their latest filing, $3.4M in all. The largest: Renaissance Technologies (1.0M shares, $1.9M), Two Sigma Investments (580K shares, $1.1M), Ken Griffin's Citadel Advisors (244K shares, $453K), Izzy Englander's Millennium Management (23K shares, $44K).

Data on this page is provided for informational purposes only and is not financial advice. See our editorial policy.