XOOMAR

Opko Health (OPK)

Opko Health on one page: short interest, daily short volume, fails to deliver, large holders, 13F holders, financials, earnings dates and insider trades. Listed on Nasdaq, classified by the SEC as pharmaceutical preparations.

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35.6M

Short interest

settlement 2026-09-30

14.9

Days to cover

+4.4 days vs prior

28.0%

Short share of volume

2026-10-09

3,327

Fails to deliver

settlement 2026-09-14

Wed 28 Oct

Next earnings

estimated date

$0

Insider flow, 90 days

0 buys, 0 sells

As of 2026-10-09.

Short interest

FINRA, twice a month. The newest 24 settlements in the table, 48 in the chart. JSON

As of 30 September 2026, short interest in OPK is 35,560,259 shares, up 1,001,887 shares over the last month. Over the last 48 readings it ranged from 30,340,574 shares (31 December 2025) to 116,494,002 shares (31 March 2025). The latest reading sits at the bottom of that range. At the reported average volume of 2.4M shares a day that is 14.9 days to cover.

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SettlementShares shortChangeAvg daily volumeDays to cover
2026-09-3035,560,259-1.2%2,379,49814.94
2026-09-1535,987,629+4.1%3,411,04810.55
2026-08-3134,558,372+2.7%2,509,99413.77
2026-08-1433,649,355+2.3%2,721,23312.37
2026-07-3132,883,700-2.3%6,096,7725.39
2026-07-1533,644,789+3.2%2,596,52312.96
2026-06-3032,594,765-0.6%3,649,8368.93
2026-06-1532,789,842-0.8%2,770,14511.84
2026-05-2933,037,706+1.2%3,027,31210.91
2026-05-1532,656,834-3.3%1,973,95816.54
2026-04-3033,763,628+2.4%2,660,21012.69
2026-04-1532,978,308-1.9%1,863,86317.69
2026-03-3133,615,361+2.6%3,079,79210.91
2026-03-1332,776,490+4.5%2,278,89014.38
2026-02-2731,374,396-1.0%1,769,54617.73
2026-02-1331,677,429+2.6%2,892,21110.95
2026-01-3030,881,465+1.2%3,683,8808.38
2026-01-1530,515,491+0.6%3,129,2879.75
2025-12-3130,340,574-6.9%4,237,2117.16
2025-12-1532,577,197+3.7%3,009,78710.82
2025-11-2831,424,789-7.1%2,867,00710.96
2025-11-1433,814,574+3.2%2,721,31412.43
2025-10-3132,755,482-1.9%1,825,50817.94
2025-10-1533,372,771-0.9%1,646,60320.27

Daily short volume

FINRA Reg SHO, the last 30 sessions. JSON

As of 9 October 2026, the short share of OPK volume is 28.0%, down 30.6 points over the last five sessions. Over the last 30 readings it ranged from 28.0% (9 October 2026) to 59.7% (10 September 2026). The latest reading sits at the bottom of that range. The latest reading is 18.1 points below the 30-session average of 46.1%, on 413K shares reported.

DateShort volumeTotal volumeShort shareExempt
2026-10-09116K413K28.0%0
2026-10-08418K863K48.5%16,400
2026-10-07259K861K30.1%4,900
2026-10-06457K1.0M44.2%12,279
2026-10-05372K745K50.0%200
2026-10-02369K629K58.6%1,000
2026-10-01560K1.1M49.6%300
2026-09-30348K983K35.4%501
2026-09-29366K809K45.2%3,150
2026-09-28213K659K32.3%23,814
2026-09-25204K662K30.8%863
2026-09-24440K1.2M35.4%5,384
2026-09-23366K719K51.0%56,602
2026-09-22562K1.6M35.8%22,187
2026-09-21325K984K33.0%1,243
2026-09-18571K1.0M55.2%77,730
2026-09-17354K627K56.4%839
2026-09-16356K764K46.6%301
2026-09-15212K521K40.6%2,457
2026-09-14571K969K59.0%67,548
2026-09-11935K2.1M45.3%910
2026-09-10382K640K59.7%3,365
2026-09-09337K715K47.2%4,688
2026-09-08491K956K51.4%4,307
2026-09-04481K818K58.8%1,300
2026-09-031.2M3.0M38.6%1,665
2026-09-021.8M3.0M58.6%444
2026-09-01654K1.1M59.3%1,390
2026-08-31560K1.1M52.1%2,304
2026-08-28501K1.1M46.3%2,034

Fails to deliver

SEC, the last 30 settlement dates with a fail. JSON

As of 14 September 2026, the fails-to-deliver balance in OPK is 3,327 shares, up 2,482 shares over the last settlement date. Over the last 30 readings it ranged from 1 share (26 August 2026) to 100,573 shares (7 August 2026). The latest reading sits at the bottom of that range.

SettlementShares failedPriceValue
2026-09-143,327$1.57$5K
2026-09-09845$1.59$1K
2026-09-025,585$1.52$8K
2026-08-3113,881$1.48$21K
2026-08-27260$1.51$393
2026-08-261$1.49$1
2026-08-2517$1.48$25
2026-08-2416,132$1.48$24K
2026-08-143,157$1.40$4K
2026-08-133,674$1.39$5K
2026-08-123,396$1.39$5K
2026-08-113,396$1.39$5K
2026-08-106,396$1.37$9K
2026-08-07100,573$1.32$133K
2026-08-068,651$1.35$12K
2026-08-052,878$1.31$4K
2026-08-0452,650$1.31$69K
2026-08-032,683$1.32$4K
2026-07-312,883$1.34$4K
2026-07-302,883$1.37$4K
2026-07-2421,256$1.17$25K
2026-07-2323,356$1.18$28K
2026-07-2223,356$1.21$28K
2026-07-2123,356$1.20$28K
2026-07-2023,356$1.19$28K
2026-07-1723,356$1.19$28K
2026-07-1623,187$1.20$28K
2026-07-1523,606$1.22$29K
2026-07-1423,612$1.23$29K
2026-07-1323,612$1.35$32K

Insider trades

SEC Form 4, newest first, 50 of 100 shown. JSON

No open-market insider trades were reported for OPK in the last 90 days. The most recent filings are listed below. Latest filing: Rubin Steven D (Executive VP-Administration) on 2026-07-24.

DateInsiderTitleTypeSharesPriceValueOwned after
2026-07-24Rubin Steven DExecutive VP-AdministrationTax withholding53K$1.22$65K6.6M
2026-07-24Logal AdamSr. Vice President, CFOTax withholding53K$1.22$65K563K
2026-03-20PAGANELLI JOHN ADirectorBuy10K$1.14$11K394K
2025-11-21Frost Gamma Investments TrustTenPercentOwnerBuy193K$1.34$258K216.7M
2025-11-21Frost Gamma Investments TrustTenPercentOwnerBuy102K$1.30$133K216.2M
2025-11-21Frost Gamma Investments TrustTenPercentOwnerBuy4K$1.32$5K216.2M
2025-11-21Frost Gamma Investments TrustTenPercentOwnerBuy191K$1.33$255K216.5M
2025-11-21Frost Gamma Investments TrustTenPercentOwnerBuy89K$1.33$119K216.3M
2025-11-21FROST PHILLIP MD ET ALCEO & ChairmanBuy193K$1.33$257K216.7M
2025-11-21FROST PHILLIP MD ET ALCEO & ChairmanBuy191K$1.33$255K216.5M
2025-11-21FROST PHILLIP MD ET ALCEO & ChairmanBuy89K$1.32$118K216.3M
2025-11-21FROST PHILLIP MD ET ALCEO & ChairmanBuy4K$1.32$5K216.2M
2025-11-21FROST PHILLIP MD ET ALCEO & ChairmanBuy102K$1.30$133K216.2M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy14K$1.35$18K216.1M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy47K$1.33$63K215.7M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy119K$1.32$157K215.7M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy212K$1.33$282K215.9M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy2K$1.35$2K216.1M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy25K$1.34$33K216.1M
2025-11-20Frost Gamma Investments TrustTenPercentOwnerBuy162K$1.34$217K216.1M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy14K$1.35$18K216.1M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy2K$1.34$2K216.1M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy25K$1.34$33K216.1M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy162K$1.33$216K216.1M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy212K$1.33$282K215.9M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy47K$1.32$62K215.7M
2025-11-20FROST PHILLIP MD ET ALCEO & ChairmanBuy119K$1.32$157K215.7M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy67K$1.31$87K215.2M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy13K$1.31$17K215.1M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy30K$1.30$39K215.1M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy155K$1.32$205K215.5M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy300$1.29$387215.1M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy58K$1.29$75K215.1M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy36K$1.28$46K215.0M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy199K$1.32$263K215.4M
2025-11-19Frost Gamma Investments TrustTenPercentOwnerBuy21K$1.30$28K215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy155K$1.32$205K215.5M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy199K$1.31$262K215.4M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy67K$1.31$87K215.2M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy13K$1.30$17K215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy30K$1.30$39K215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy21K$1.29$28K215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy300$1.29$387215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy58K$1.28$75K215.1M
2025-11-19FROST PHILLIP MD ET ALCEO & ChairmanBuy36K$1.28$46K215.0M
2025-11-18Frost Gamma Investments TrustTenPercentOwnerBuy428$1.28$548214.8M
2025-11-18Frost Gamma Investments TrustTenPercentOwnerBuy70K$1.28$89K214.8M
2025-11-18Frost Gamma Investments TrustTenPercentOwnerBuy84K$1.29$108K214.9M
2025-11-18Frost Gamma Investments TrustTenPercentOwnerBuy1$1.29$1214.9M
2025-11-18Frost Gamma Investments TrustTenPercentOwnerBuy34K$1.29$43K215.0M

Form 4 filings are due within two business days of the trade. Insiders sell for many reasons that say nothing about the company; open-market buys are rarer.

Large holders (13D and 13G)

One row per reporting person with its latest filing, newest first. JSON

2 holders report 5% or more of OPK in their latest filing, all on Schedule 13D (active intent). The largest reported stake is FROST PHILLIP MD ET AL at 34.1% of the class (255,429,406 shares), filed 2026-07-01 for an event on 2026-06-29.

FiledFormHolderSharesOf classEvent
2026-07-0113D/Ano. 28FROST PHILLIP MD ET ALindividual255.4M34.1%2026-06-29
2026-07-0113D/Ano. 28Frost Gamma Investments Trustother entity216.7M29.0%2026-06-29
2026-07-0113D/Ano. 28Frost Nevada Investments Trustother entity30.1M4.0%2026-06-29

13F holders

Tracked managers holding OPK at their latest 13F. JSON

5 of the 30 tracked managers held OPK at their latest 13F, $4.6M in total at quarter-end prices. Citadel Advisors is the largest at $2.1M (0.0% of its portfolio) as of 2026-06-30. Over the prior quarter 4 added shares and 1 cut.

FundQuarterSharesValueOf portfolioChange in shares
Citadel Advisors2026-06-301.4M$2.1M0.00%-659K
AQR Capital Management2026-06-301.2M$1.9M0.00%+476K
Two Sigma Investments2026-06-30176K$264K0.00%+6K
Point72 Asset Management2026-06-30145K$218K0.00%+52K
Millennium Management2026-06-3072K$108K0.00%new

Only the 30 tracked managers on the funds hub; a 13F reports long positions in US listed stock at quarter end, 45 days late, and says nothing about shorts or positions sold since.

Financials

SEC XBRL, as filed. JSON

In Q2 FY 2026 (quarter ended 2026-06-30) Opko Health reported revenue of $163.6M, up 4.3% from the same quarter a year earlier, and net loss of $8.4M (-0.01 diluted EPS). In FY 2025 it generated -$178.5M of operating cash flow and spent $47.0M on buybacks. As of 2026-06-30, cash was $300.8M against $349.1M of debt.

Cash
$300.8M
Debt
$349.1M
Equity
$1.18B
Total assets
$1.83B
Shares outstanding
746,328,225

Quarterly, last 8 quarters

QuarterPeriod endRevenueNet incomeMarginDiluted EPS
Q2 FY 20262026-06-30$163.6M-$8.4M-5.1%-0.01
Q1 FY 20262026-03-31$124.2M-$54.8M-44.2%-0.07
Q4 FY 20252025-12-31$148.5M-$31.3M-21.1%-0.04
Q3 FY 20252025-09-30$151.7M$21.6M14.3%0.03
Q2 FY 20252025-06-30$156.8M-$148.4M-94.7%-0.19
Q1 FY 20252025-03-31$150.0M-$67.6M-45.1%-0.10
Q4 FY 20242024-12-31$183.6M$14.0M7.6%0.01
Q3 FY 20242024-09-30$173.6M$24.9M14.3%0.03

Fiscal years, with buybacks and dividends

Fiscal yearEndsRevenueNet incomeOperating cash flowCapexBuybacksDividends
FY 20252025-12-31$606.9M-$225.7M-$178.5M$12.3M$47.0Mn/a
FY 20242024-12-31$713.1M-$53.2M-$183.5M$25.0M$90.2Mn/a
FY 20232023-12-31$863.5M-$188.9M-$28.2M$16.3M$0n/a
FY 20222022-12-31$1.00B-$328.4M-$95.2M$24.6M$0n/a
FY 20212021-12-31$1.77B-$30.1M$38.3M$32.2Mn/an/a

Quarters are the three-month figures the company reports; a fourth quarter marked derived is the fiscal year less the three reported quarters, since companies report it only inside the 10-K. Fiscal years are the annual figures. Buybacks are the cash the company paid to repurchase its common stock in the year, not the amount authorized. Balance sheet lines are as of 2026-06-30; shares outstanding as of 2026-07-17 from the cover page.

What this page is

Opko Health in the regulatory record

Regulators publish company data in separate files that never sit next to each other: FINRA's twice-monthly short interest, its daily short sale volume, the SEC's fails-to-deliver counts, and each insider's Form 4. A company page puts those series for one ticker on one URL, with planned sales, large holders, 13F holders and financials beside them, so the short position, the daily flow, the settlement fails and what insiders are doing can be read together.

Each section has its own history table, a one-line summary of the latest figures and its own JSON and CSV links, and says when its source last updated.

This page follows Opko Health (OPK), SEC CIK 944809, listed on Nasdaq, classified by the SEC as pharmaceutical preparations. The cross-market tables live on the short interest and insider transactions hubs.

Source and updates

Short interest
FINRA consolidated short interestSource: FINRA.Twice a month, about eight business days after settlement. Latest 2026-09-30.JSON and CSV
Daily short volume
FINRA Reg SHO daily filesSource: FINRA.Every trading day, the morning after FINRA posts it. Latest 2026-10-09.JSON and CSV
Fails to deliver
SEC fails-to-deliver dataSource: SEC.Twice a month, a few weeks after the half month ends. Latest 2026-09-14.JSON and CSV
Large holders
SEC EDGAR Schedule 13D and 13GSource: SEC.New filings appear shortly after the SEC posts them. A 13D is due within five business days of crossing 5%; a 13G follows the passive schedule. Latest 2026-07-01.JSON and CSV
13F holders
SEC EDGAR Form 13F-HRSource: SEC.Quarterly, filed within 45 days of quarter end; 30 tracked managers. Latest 2026-06-30.JSON and CSV
Financials
SEC EDGAR 10-K and 10-Q filingsSource: SEC.Weekly; values are as filed in the 10-Q and 10-K. Latest 2026-06-30.JSON and CSV
Earnings dates
SEC EDGAR 8-K filings (Item 2.02)Source: SEC.Twice a day. Reported dates come from the company's 8-K filings; the next date is marked as an estimate until the 8-K arrives. Latest 2026-07-27.JSON and CSV
Insider trades
SEC EDGAR Form 4Source: SEC.New filings appear shortly after the SEC posts them; they're due two business days after the trade. Latest 2026-07-24.JSON and CSV
Company record
EDGAR filing index for CIK 944809Ticker, name and exchange from the SEC's company list, refreshed weekly.
Rate limits
10 requests a minute without a key, 30 with a free key from a free account.

How to read it

  • Read the position against the flow: rising short interest with a high daily short share is new shorting; rising short interest with a normal short share is old shorts holding on.
  • Insider buys next to a large short position are rare and stand out; insider sells next to one are common and mean little.
  • Fails to deliver matter relative to the float, not in absolute shares; a million failed shares in a mega cap is noise.

Analysis of what the data shows, not advice. XOOMAR does not recommend buying, selling or holding anything.

Datasets

Frequently Asked Questions

How much of OPK is sold short?
35,560,259 shares were held short at the 2026-09-30 settlement, 14.9 days of average volume. FINRA publishes the next count about eight business days after the 15th and the last business day of the month.
What is OPK's daily short volume?
On 2026-10-09, 115,632 of the 412,712 OPK shares reported to FINRA were sold short, 28.0% of the day's reported volume. Short volume is a flow for one day, not a position.
Does OPK have fails to deliver?
The SEC's latest file shows 3,327 OPK shares failed to deliver at settlement 2026-09-14. Fails are reported per settlement date and published twice a month with a lag.
Are OPK insiders buying or selling?
No open-market insider trades were reported for OPK in the last 90 days. The most recent filings are listed below. Latest filing: Rubin Steven D (Executive VP-Administration) on 2026-07-24.
Who owns 5% or more of OPK?
2 holders report 5% or more of OPK in their latest filing, all on Schedule 13D (active intent). The largest reported stake is FROST PHILLIP MD ET AL at 34.1% of the class (255,429,406 shares), filed 2026-07-01 for an event on 2026-06-29.
What did OPK report last quarter?
In Q2 FY 2026 (quarter ended 2026-06-30) Opko Health reported revenue of $163.6M, up 4.3% from the same quarter a year earlier, and net loss of $8.4M (-0.01 diluted EPS). In FY 2025 it generated -$178.5M of operating cash flow and spent $47.0M on buybacks. As of 2026-06-30, cash was $300.8M against $349.1M of debt.
Which tracked 13F managers own OPK?
5 of the 30 tracked 13F managers held OPK shares at their latest filing, $4.6M in all. The largest: Ken Griffin's Citadel Advisors (1.4M shares, $2.1M), Cliff Asness's AQR Capital Management (1.2M shares, $1.9M), Two Sigma Investments (176K shares, $264K), Steve Cohen's Point72 Asset Management (145K shares, $218K), Izzy Englander's Millennium Management (72K shares, $108K).

Data on this page is provided for informational purposes only and is not financial advice. See our editorial policy.